The dopamine receptor D4 regulates the proliferation of pulmonary arteries smooth muscle in broilers by downregulating AT1R

The dopamine receptor D4 regulates the proliferation of pulmonary arteries smooth muscle in broilers by downregulating AT1R

Abstract The major cause of pulmonary vascular remodeling in broilers is abnormal proliferation of vascular smooth muscle cells (VSMCs), and one of the main causes of pulmonary hypertension syndrome (PHS) in broilers is pulmonary artery vascular remodeling. Forty Arbor Acres (AA) broilers were rando...

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Bibliographic Details
Main Authors: Xiaoqi Yang, Yang Fu, Lianfeng Wu, Antong Li, Luyao Ji, Hao Li, Yuxuan Peng, Jiabin Zhang, Donghai Zhou, Huiping Zhou
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Animal Diseases
Subjects:
AT1 receptors
Dopamine receptor D4
PHS
Vascular smooth muscle
Angiotensin II
Online Access:https://doi.org/10.1186/s44149-021-00012-w

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