Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study
Background: Little is known about the relationship of depression with incident cardiovascular disease (CVD) among American Indians (AIs), a population with a high burden of depressive symptoms and CVD. In this study, we examined the association of depressive symptoms with CVD risk among AIs and asse...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Psychiatry Research Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772598723000247 |
| _version_ | 1797810591909281792 |
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| author | Torrie Eagle Staff Marcia O'Leary Amanda M. Fretts |
| author_facet | Torrie Eagle Staff Marcia O'Leary Amanda M. Fretts |
| author_sort | Torrie Eagle Staff |
| collection | DOAJ |
| description | Background: Little is known about the relationship of depression with incident cardiovascular disease (CVD) among American Indians (AIs), a population with a high burden of depressive symptoms and CVD. In this study, we examined the association of depressive symptoms with CVD risk among AIs and assessed whether an objective marker of ambulatory activity influenced the relationship. Methods: The study comprised participants from the Strong Heart Family Study, a longitudinal study of CVD risk among AIs free of CVD at baseline (2001–2003) and who participated in a follow-up examination (n = 2209). The Center for Epidemiologic Studies of Depression Scale (CES-D) was used to assess depressive symptoms and depressive affect. Ambulatory activity was measured using Accusplit AE120 pedometers. Incident CVD was defined as new myocardial infarction, coronary heart disease, or stroke (through 2017). Generalized estimating equations were used to examine the association of depressive symptoms with incident CVD. Results: 27.5% of participants reported moderate or severe depressive symptoms at baseline and 262 participants developed CVD during follow-up. Compared to participants who reported no depressive symptoms, the odds ratios for developing CVD among those who reported mild, moderate, or severe symptoms were: 1.19 (95% CI: 0.76, 1.85), 1.61 (95% CI: 1.09, 2.37), and 1.71 (95% CI: 1.01, 2.91), respectively. Adjustment for activity did not alter findings. Limitations: CES-D is a tool used to identify individuals with depressive symptoms and not a measure of clinical depression. Conclusion: Higher levels of reported depressive symptoms were positively associated with CVD risk in a large cohort of AIs. |
| first_indexed | 2024-03-13T07:11:11Z |
| format | Article |
| id | doaj.art-c703f861cc064f58bbab33619355ee9e |
| institution | Directory Open Access Journal |
| issn | 2772-5987 |
| language | English |
| last_indexed | 2024-03-13T07:11:11Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Psychiatry Research Communications |
| spelling | doaj.art-c703f861cc064f58bbab33619355ee9e2023-06-06T04:01:02ZengElsevierPsychiatry Research Communications2772-59872023-06-0132100125Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family studyTorrie Eagle Staff0Marcia O'Leary1Amanda M. Fretts2Missouri Breaks Industries Research Inc, Eagle Butte, SD, USA; Northwest Portland Area Indian Health Board, Portland, OR, USAMissouri Breaks Industries Research Inc, Eagle Butte, SD, USAUniversity of Washington Department of Epidemiology, Seattle, WA, USA; Corresponding author. University of Washington, Department of Epidemiology, 3980 15th Ave NE Box 351619, Seattle, WA, 98101, USA.Background: Little is known about the relationship of depression with incident cardiovascular disease (CVD) among American Indians (AIs), a population with a high burden of depressive symptoms and CVD. In this study, we examined the association of depressive symptoms with CVD risk among AIs and assessed whether an objective marker of ambulatory activity influenced the relationship. Methods: The study comprised participants from the Strong Heart Family Study, a longitudinal study of CVD risk among AIs free of CVD at baseline (2001–2003) and who participated in a follow-up examination (n = 2209). The Center for Epidemiologic Studies of Depression Scale (CES-D) was used to assess depressive symptoms and depressive affect. Ambulatory activity was measured using Accusplit AE120 pedometers. Incident CVD was defined as new myocardial infarction, coronary heart disease, or stroke (through 2017). Generalized estimating equations were used to examine the association of depressive symptoms with incident CVD. Results: 27.5% of participants reported moderate or severe depressive symptoms at baseline and 262 participants developed CVD during follow-up. Compared to participants who reported no depressive symptoms, the odds ratios for developing CVD among those who reported mild, moderate, or severe symptoms were: 1.19 (95% CI: 0.76, 1.85), 1.61 (95% CI: 1.09, 2.37), and 1.71 (95% CI: 1.01, 2.91), respectively. Adjustment for activity did not alter findings. Limitations: CES-D is a tool used to identify individuals with depressive symptoms and not a measure of clinical depression. Conclusion: Higher levels of reported depressive symptoms were positively associated with CVD risk in a large cohort of AIs.http://www.sciencedirect.com/science/article/pii/S2772598723000247Cardiovascular diseaseDepressionPhysical activityAmerican IndiansCohort study |
| spellingShingle | Torrie Eagle Staff Marcia O'Leary Amanda M. Fretts Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study Psychiatry Research Communications Cardiovascular disease Depression Physical activity American Indians Cohort study |
| title | Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study |
| title_full | Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study |
| title_fullStr | Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study |
| title_full_unstemmed | Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study |
| title_short | Depression, physical activity, and incident cardiovascular disease among American Indians: The strong heart family study |
| title_sort | depression physical activity and incident cardiovascular disease among american indians the strong heart family study |
| topic | Cardiovascular disease Depression Physical activity American Indians Cohort study |
| url | http://www.sciencedirect.com/science/article/pii/S2772598723000247 |
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