Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis.

Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis.

BACKGROUND: The mitochondrial (mt) displacement loop (D-loop) is known to accumulate structural alterations and mutations. The aim of this study was to investigate the prevalence of single nucleotide polymorphisms (SNPs) within the D-loop among chronic dialysis patients and healthy controls. METHODO...

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Main Authors: Jin-Bor Chen, Yi-Hsin Yang, Wen-Chin Lee, Chia-Wei Liou, Tsu-Kung Lin, Yueh-Hua Chung, Li-Yeh Chuang, Cheng-Hong Yang, Hsueh-Wei Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399812?pdf=render

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