Divergent molecular events underlying initial T-cell commitment in human prenatal and postnatal thymus

Divergent molecular events underlying initial T-cell commitment in human prenatal and postnatal thymus

IntroductionIntrathymic T-cell development is a coordinated process accompanied by dynamic changes in gene expression. Although the transcriptome characteristics of developing T cells in both human fetal and postnatal thymus at single-cell resolution have been revealed recently, the differences betw...

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Bibliographic Details
Main Authors:	Han He, Yingpeng Yao, Lindong Tang, Yuhui Li, Zongcheng Li, Bing Liu, Yu Lan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Series:	Frontiers in Immunology
Subjects:	human thymus scRNA-seq T cell development double-negative thymocytes alternative polyadenylation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1240859/full

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