Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy

Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy

Pathological retinal angiogenesis contributes to the pathogenesis of several ocular diseases. Valproic acid, a widely used antiepileptic drug, exerts anti-angiogenic effects by inhibiting histone deacetylase (HDAC). Herein, we investigated the effects of valproic acid and vorinostat, a HDAC inhibito...

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Bibliographic Details
Main Authors:	Naoto Iizuka, Akane Morita, Chihiro Kawano, Asami Mori, Kenji Sakamoto, Masakazu Kuroyama, Kunio Ishii, Tsutomu Nakahara
Format:	Article
Language:	English
Published:	Elsevier 2018-11-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861318301890

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