Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis

Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis

Allergic rhinitis (AR) is globally prevalent and its pathogenesis remains unclear. Alternative activation of macrophages is suggested in AR and thought to be involved in natural immunoregulatory processes in AR. Aberrant activation of Nod-like receptor protein 3 (NLRP3) inflammasome is linked with A...

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Bibliographic Details
Main Authors: Beibei Wo, Chunyang Du, Yan Yang, Huimin Qi, Zihui Liang, Conghui He, Fang Yao, Xiaoming Li
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Allergic rhinitis
Nod-like receptor protein 3 (NLRP3)
Immunity-related GTPase M (IRGM)
Human placenta extract (HPE)
Macrophages polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223001518

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http://www.sciencedirect.com/science/article/pii/S0753332223001518

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