Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses

Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses

Summary: Recognition of the components of Mycobacterium tuberculosis (Mtb) by macrophages is vital for initiating a cascade of host immune responses. However, the recognition of Mtb-secretory proteins by the receptor-independent pathways of the host remains unclear. Rv1804c is a highly conserved sec...

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Bibliographic Details
Main Authors:	Jianjian Zheng, Chunsheng Dong, Sidong Xiong
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	iScience
Subjects:	Immunology Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224003225

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