Influence of 24 h Simulated Altitude on Red Blood Cell Deformability and Hematological Parameters in Patients with Fontan Circulation

Influence of 24 h Simulated Altitude on Red Blood Cell Deformability and Hematological Parameters in Patients with Fontan Circulation

Patients with Fontan circulation are particularly dependent on low pulmonary vascular resistance because their lungs are passively perfused. Hypoxia drives pulmonary vasoconstriction; thus, red blood cell (RBC) deformability and stability of hematological parameters might be of particular importance...

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Bibliographic Details
Main Authors: Julian Alexander Härtel, Nicole Müller, Johannes Breuer, Jens Jordan, Jens Tank, Janina Bros, Benedikt Seeger, Emily Zollmann, Wilhelm Bloch, Marijke Grau
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
red blood cells
Fontan circulation
hypoxia
hemorheology
RBC deformability
congenital heart defect
Online Access:https://www.mdpi.com/2218-1989/12/11/1025

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