Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review
AimsTo perform a systematic review assessing the clinical manifestations and outcomes of cardiorenal syndrome or the presence of both cardiac and renal complications in the 2019 coronavirus disease (COVID-19) patients.MethodsAll relevant studies about cardiorenal syndrome or both cardiac and renal c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.915533/full |
| _version_ | 1811237708768477184 |
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| author | Ling Lin Yangqin Chen Dongwan Han Andrew Yang Andrew Yang Amanda Y. Wang Amanda Y. Wang Amanda Y. Wang Wenjie Qi |
| author_facet | Ling Lin Yangqin Chen Dongwan Han Andrew Yang Andrew Yang Amanda Y. Wang Amanda Y. Wang Amanda Y. Wang Wenjie Qi |
| author_sort | Ling Lin |
| collection | DOAJ |
| description | AimsTo perform a systematic review assessing the clinical manifestations and outcomes of cardiorenal syndrome or the presence of both cardiac and renal complications in the 2019 coronavirus disease (COVID-19) patients.MethodsAll relevant studies about cardiorenal syndrome or both cardiac and renal complications in COVID-19 patients were retrieved on PUBMED, MEDLINE, and EMBASE from December 1, 2019 to February 20, 2022.ResultsOur search identified 15 studies including 637 patients with a diagnosis of cardiorenal syndrome or evidence of both cardiac and renal complications followingSARS-CoV-2 infection. They were male predominant (66.2%, 422/637), with a mean age of 58 years old. Cardiac complications included myocardial injury (13 studies), heart failure (7 studies), arrhythmias (5 studies), or myocarditis and cardiomyopathy (2 studies). Renal complications manifested as acute kidney injury with or without oliguria. Patients with cardiorenal injury were often associated with significantly elevated levels of inflammatory markers (CRP, PCT, IL-6). Patients with a diagnosis of cardiorenal syndrome or evidence of both cardiac and renal complications had more severe disease and poorer prognosis (9 studies).ConclusionThe presence of either cardiorenal syndrome or concurrent cardiac and renal complications had a significant impact on the severity of the disease and the mortality rate among patients with COVID-19 infection. Therefore, careful assessment and management of potential cardiac and renal complications in patients with COVID-19 infection are important to improve their outcomes. |
| first_indexed | 2024-04-12T12:29:03Z |
| format | Article |
| id | doaj.art-c729ec642e094cd38f4eb731644616ee |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T12:29:03Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-c729ec642e094cd38f4eb731644616ee2022-12-22T03:33:05ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-06-01910.3389/fcvm.2022.915533915533Cardiorenal Syndrome in COVID-19 Patients: A Systematic ReviewLing Lin0Yangqin Chen1Dongwan Han2Andrew Yang3Andrew Yang4Amanda Y. Wang5Amanda Y. Wang6Amanda Y. Wang7Wenjie Qi8Department of Infectious Disease, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Infectious Disease, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Infectious Disease, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of General and Acute Care Medicine, Royal North Shore Hospital, Sydney, NSW, AustraliaConcord Clinical School, The University of Sydney, Sydney, NSW, AustraliaConcord Clinical School, The University of Sydney, Sydney, NSW, AustraliaDivision of the Renal and Metabolic, George Institute for Global Health, TheUniversity of New South Wales, Sydney, NSW, AustraliaDepartment of Renal Medicine, Concord Repatriation General Hospital, Concord, NSW, AustraliaDepartment of Infectious Disease, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaAimsTo perform a systematic review assessing the clinical manifestations and outcomes of cardiorenal syndrome or the presence of both cardiac and renal complications in the 2019 coronavirus disease (COVID-19) patients.MethodsAll relevant studies about cardiorenal syndrome or both cardiac and renal complications in COVID-19 patients were retrieved on PUBMED, MEDLINE, and EMBASE from December 1, 2019 to February 20, 2022.ResultsOur search identified 15 studies including 637 patients with a diagnosis of cardiorenal syndrome or evidence of both cardiac and renal complications followingSARS-CoV-2 infection. They were male predominant (66.2%, 422/637), with a mean age of 58 years old. Cardiac complications included myocardial injury (13 studies), heart failure (7 studies), arrhythmias (5 studies), or myocarditis and cardiomyopathy (2 studies). Renal complications manifested as acute kidney injury with or without oliguria. Patients with cardiorenal injury were often associated with significantly elevated levels of inflammatory markers (CRP, PCT, IL-6). Patients with a diagnosis of cardiorenal syndrome or evidence of both cardiac and renal complications had more severe disease and poorer prognosis (9 studies).ConclusionThe presence of either cardiorenal syndrome or concurrent cardiac and renal complications had a significant impact on the severity of the disease and the mortality rate among patients with COVID-19 infection. Therefore, careful assessment and management of potential cardiac and renal complications in patients with COVID-19 infection are important to improve their outcomes.https://www.frontiersin.org/articles/10.3389/fcvm.2022.915533/fullcardiorenal syndrome (CRS)COVID-19SARS-CoV-2cardiac complicationsrenal complications |
| spellingShingle | Ling Lin Yangqin Chen Dongwan Han Andrew Yang Andrew Yang Amanda Y. Wang Amanda Y. Wang Amanda Y. Wang Wenjie Qi Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review Frontiers in Cardiovascular Medicine cardiorenal syndrome (CRS) COVID-19 SARS-CoV-2 cardiac complications renal complications |
| title | Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review |
| title_full | Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review |
| title_fullStr | Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review |
| title_full_unstemmed | Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review |
| title_short | Cardiorenal Syndrome in COVID-19 Patients: A Systematic Review |
| title_sort | cardiorenal syndrome in covid 19 patients a systematic review |
| topic | cardiorenal syndrome (CRS) COVID-19 SARS-CoV-2 cardiac complications renal complications |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.915533/full |
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