Comparative analysis of prophage-like elements in Helicobacter sp. genomes
Prophages are regarded as one of the factors underlying bacterial virulence, genomic diversification, and fitness, and are ubiquitous in bacterial genomes. Information on Helicobacter sp. prophages remains scarce. In this study, sixteen prophages were identified and analyzed in detail. Eight of them...
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PeerJ Inc.
2016-05-01
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| Online Access: | https://peerj.com/articles/2012.pdf |
| _version_ | 1797417898337107968 |
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| author | Xiangyu Fan Yumei Li Rong He Qiang Li Wenxing He |
| author_facet | Xiangyu Fan Yumei Li Rong He Qiang Li Wenxing He |
| author_sort | Xiangyu Fan |
| collection | DOAJ |
| description | Prophages are regarded as one of the factors underlying bacterial virulence, genomic diversification, and fitness, and are ubiquitous in bacterial genomes. Information on Helicobacter sp. prophages remains scarce. In this study, sixteen prophages were identified and analyzed in detail. Eight of them are described for the first time. Based on a comparative genomic analysis, these sixteen prophages can be classified into four different clusters. Phylogenetic relationships of Cluster A Helicobacter prophages were investigated. Furthermore, genomes of Helicobacter prophages from Clusters B, C, and D were analyzed. Interestingly, some putative antibiotic resistance proteins and virulence factors were associated with Helicobacter prophages. |
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| format | Article |
| id | doaj.art-c72a7c7584d24e31816d42faf3e42cf6 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:25:10Z |
| publishDate | 2016-05-01 |
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| spelling | doaj.art-c72a7c7584d24e31816d42faf3e42cf62023-12-03T11:21:34ZengPeerJ Inc.PeerJ2167-83592016-05-014e201210.7717/peerj.2012Comparative analysis of prophage-like elements in Helicobacter sp. genomesXiangyu Fan0Yumei Li1Rong He2Qiang Li3Wenxing He4School of Biological Science and Technology, University of Jinan, Jinan, ChinaSchool of Biological Science and Technology, University of Jinan, Jinan, ChinaSchool of Biological Science and Technology, University of Jinan, Jinan, ChinaSchool of Biological Science and Technology, University of Jinan, Jinan, ChinaSchool of Biological Science and Technology, University of Jinan, Jinan, ChinaProphages are regarded as one of the factors underlying bacterial virulence, genomic diversification, and fitness, and are ubiquitous in bacterial genomes. Information on Helicobacter sp. prophages remains scarce. In this study, sixteen prophages were identified and analyzed in detail. Eight of them are described for the first time. Based on a comparative genomic analysis, these sixteen prophages can be classified into four different clusters. Phylogenetic relationships of Cluster A Helicobacter prophages were investigated. Furthermore, genomes of Helicobacter prophages from Clusters B, C, and D were analyzed. Interestingly, some putative antibiotic resistance proteins and virulence factors were associated with Helicobacter prophages.https://peerj.com/articles/2012.pdfHelicobacterProphagePhylogenyComparative genomics |
| spellingShingle | Xiangyu Fan Yumei Li Rong He Qiang Li Wenxing He Comparative analysis of prophage-like elements in Helicobacter sp. genomes PeerJ Helicobacter Prophage Phylogeny Comparative genomics |
| title | Comparative analysis of prophage-like elements in Helicobacter sp. genomes |
| title_full | Comparative analysis of prophage-like elements in Helicobacter sp. genomes |
| title_fullStr | Comparative analysis of prophage-like elements in Helicobacter sp. genomes |
| title_full_unstemmed | Comparative analysis of prophage-like elements in Helicobacter sp. genomes |
| title_short | Comparative analysis of prophage-like elements in Helicobacter sp. genomes |
| title_sort | comparative analysis of prophage like elements in helicobacter sp genomes |
| topic | Helicobacter Prophage Phylogeny Comparative genomics |
| url | https://peerj.com/articles/2012.pdf |
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