Molecular chaperones and proteostasis regulation during redox imbalance
Free radicals originate from both exogenous environmental sources and as by-products of the respiratory chain and cellular oxygen metabolism. Sustained accumulation of free radicals, beyond a physiological level, induces oxidative stress that is harmful for the cellular homeodynamics as it promotes...
Main Authors: | Katerina Niforou, Christina Cheimonidou, Ioannis P. Trougakos |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-01-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231714000329 |
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