Molecular chaperones and proteostasis regulation during redox imbalance

Molecular chaperones and proteostasis regulation during redox imbalance

Free radicals originate from both exogenous environmental sources and as by-products of the respiratory chain and cellular oxygen metabolism. Sustained accumulation of free radicals, beyond a physiological level, induces oxidative stress that is harmful for the cellular homeodynamics as it promotes...

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Bibliographic Details
Main Authors:	Katerina Niforou, Christina Cheimonidou, Ioannis P. Trougakos
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	Redox Biology
Subjects:	Chaperones Diseases Free radicals Oxidative stress Proteome Redox signalling
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231714000329

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