Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms
<p>Abstract</p> <p>Background</p> <p>A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identical by descent) on phenoty...
Main Authors: | Simonson Matthew A, Howrigan Daniel P, Keller Matthew C |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-09-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/12/460 |
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