Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents

Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents

The modular synthesis of the guanidine core by guanylation reactions using commercially available ZnEt<sub>2</sub> as a catalyst has been exploited as a tool for the rapid development of antitumoral guanidine candidates. Therefore, a series of phenyl-guanidines were straightforwardly obt...

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Bibliographic Details
Main Authors: Almudena del Campo-Balguerías, Blanca Parra-Cadenas, Cristina Nieto-Jimenez, Iván Bravo, Consuelo Ripoll, Elisa Poyatos-Racionero, Pawel Gancarski, Fernando Carrillo-Hermosilla, Carlos Alonso-Moreno, Alberto Ocaña
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
guanidines
guanylation reactions
high-throughput testing
Online Access:https://www.mdpi.com/1422-0067/24/18/13820

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