Glutathione Transferase P1: Potential Therapeutic Target in Ovarian Cancer

Glutathione Transferase P1: Potential Therapeutic Target in Ovarian Cancer

Chemotherapy resistance of ovarian cancer, regarded as the most lethal malignant gynecological disease, can be explained by several mechanisms, including increased activity of efflux transporters leading to decreased intracellular drug accumulation, increased efflux of the therapeutic agents from th...

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Bibliographic Details
Main Authors: Petar Simic, Igor Pljesa, Lazar Nejkovic, Djurdja Jerotic, Vesna Coric, Jelena Stulic, Nenad Kokosar, Dunja Popov, Ana Savic-Radojevic, Vladimir Pazin, Marija Pljesa-Ercegovac
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medicina
Subjects:
ovarian cancer
chemoresistance
glutathione S transferase P1
microRNA
apoptosis
Online Access:https://www.mdpi.com/1648-9144/58/11/1660

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