Layered Double Hydroxide-Based Nanocarriers for Drug Delivery
Biocompatible clay materials have attracted particular attention as the efficient drug delivery systems (DDS). In this article, we review developments in the use of layered double hydroxides (LDHs) for controlled drug release and delivery. We show how advances in the ability to synthesize intercalat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-06-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1999-4923/6/2/298 |
| _version_ | 1828137667147071488 |
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| author | Xue Bi Hui Zhang Liguang Dou |
| author_facet | Xue Bi Hui Zhang Liguang Dou |
| author_sort | Xue Bi |
| collection | DOAJ |
| description | Biocompatible clay materials have attracted particular attention as the efficient drug delivery systems (DDS). In this article, we review developments in the use of layered double hydroxides (LDHs) for controlled drug release and delivery. We show how advances in the ability to synthesize intercalated structures have a significant influence on the development of new applications of these materials. We also show how modification and/or functionalization can lead to new biotechnological and biomedical applications. This review highlights the most recent progresses in research on LDH-based controlled drug delivery systems, focusing mainly on: (i) DDS with cardiovascular drugs as guests; (ii) DDS with anti-inflammatory drugs as guests; and (iii) DDS with anti-cancer drugs as guests. Finally, future prospects for LDH-based drug carriers are also discussed. |
| first_indexed | 2024-04-11T18:23:37Z |
| format | Article |
| id | doaj.art-c72f3107f14e4bd6b4e147a0d2e79a68 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-04-11T18:23:37Z |
| publishDate | 2014-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-c72f3107f14e4bd6b4e147a0d2e79a682022-12-22T04:09:42ZengMDPI AGPharmaceutics1999-49232014-06-016229833210.3390/pharmaceutics6020298pharmaceutics6020298Layered Double Hydroxide-Based Nanocarriers for Drug DeliveryXue Bi0Hui Zhang1Liguang Dou2State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, P.O. Box 98, Beijing 100029, ChinaState Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, P.O. Box 98, Beijing 100029, ChinaState Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, P.O. Box 98, Beijing 100029, ChinaBiocompatible clay materials have attracted particular attention as the efficient drug delivery systems (DDS). In this article, we review developments in the use of layered double hydroxides (LDHs) for controlled drug release and delivery. We show how advances in the ability to synthesize intercalated structures have a significant influence on the development of new applications of these materials. We also show how modification and/or functionalization can lead to new biotechnological and biomedical applications. This review highlights the most recent progresses in research on LDH-based controlled drug delivery systems, focusing mainly on: (i) DDS with cardiovascular drugs as guests; (ii) DDS with anti-inflammatory drugs as guests; and (iii) DDS with anti-cancer drugs as guests. Finally, future prospects for LDH-based drug carriers are also discussed.http://www.mdpi.com/1999-4923/6/2/298layered double hydroxidesdrug delivery systemcontrolled releaseintercalation assemblycardiovascular druganti-inflammatory druganti-cancer drug |
| spellingShingle | Xue Bi Hui Zhang Liguang Dou Layered Double Hydroxide-Based Nanocarriers for Drug Delivery Pharmaceutics layered double hydroxides drug delivery system controlled release intercalation assembly cardiovascular drug anti-inflammatory drug anti-cancer drug |
| title | Layered Double Hydroxide-Based Nanocarriers for Drug Delivery |
| title_full | Layered Double Hydroxide-Based Nanocarriers for Drug Delivery |
| title_fullStr | Layered Double Hydroxide-Based Nanocarriers for Drug Delivery |
| title_full_unstemmed | Layered Double Hydroxide-Based Nanocarriers for Drug Delivery |
| title_short | Layered Double Hydroxide-Based Nanocarriers for Drug Delivery |
| title_sort | layered double hydroxide based nanocarriers for drug delivery |
| topic | layered double hydroxides drug delivery system controlled release intercalation assembly cardiovascular drug anti-inflammatory drug anti-cancer drug |
| url | http://www.mdpi.com/1999-4923/6/2/298 |
| work_keys_str_mv | AT xuebi layereddoublehydroxidebasednanocarriersfordrugdelivery AT huizhang layereddoublehydroxidebasednanocarriersfordrugdelivery AT liguangdou layereddoublehydroxidebasednanocarriersfordrugdelivery |