Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i>
In this study, we analyzed the organization of urocortin 3 (Ucn3)-expressing neuronal populations in the brain of the adult sea lamprey by means of in situ hybridization. We also studied the brain of larval sea lampreys to establish whether this prosocial neuropeptide is expressed differentially in...
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MDPI AG
2021-09-01
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| Online Access: | https://www.mdpi.com/2079-7737/10/10/978 |
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| author | Daniel Sobrido-Cameán Ramón Anadón Antón Barreiro-Iglesias |
| author_facet | Daniel Sobrido-Cameán Ramón Anadón Antón Barreiro-Iglesias |
| author_sort | Daniel Sobrido-Cameán |
| collection | DOAJ |
| description | In this study, we analyzed the organization of urocortin 3 (Ucn3)-expressing neuronal populations in the brain of the adult sea lamprey by means of in situ hybridization. We also studied the brain of larval sea lampreys to establish whether this prosocial neuropeptide is expressed differentially in two widely different phases of the sea lamprey life cycle. In adult sea lampreys, Ucn3 transcript expression was observed in neurons of the striatum, prethalamus, nucleus of the medial longitudinal fascicle, torus semicircularis, isthmic reticular formation, interpeduncular nucleus, posterior rhombencephalic reticular formation and nucleus of the solitary tract. Interestingly, in larval sea lampreys, only three regions showed Ucn3 expression, namely the prethalamus, the nucleus of the medial longitudinal fascicle and the posterior rhombencephalic reticular formation. A comparison with distributions of Ucn3 in other vertebrates revealed poor conservation of Ucn3 expression during vertebrate evolution. The large qualitative differences in Ucn3 expression observed between larval and adult phases suggest that the maturation of neuroregulatory circuits in the striatum, torus semicircularis and hindbrain chemosensory systems is closely related to profound life-style changes occurring after the transformation from larval to adult life. |
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| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-10T06:43:46Z |
| publishDate | 2021-09-01 |
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| spelling | doaj.art-c730f93c95664b149986f0040ddc8e7c2023-11-22T17:27:51ZengMDPI AGBiology2079-77372021-09-01101097810.3390/biology10100978Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i>Daniel Sobrido-Cameán0Ramón Anadón1Antón Barreiro-Iglesias2Department of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, SpainDepartment of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, SpainDepartment of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, SpainIn this study, we analyzed the organization of urocortin 3 (Ucn3)-expressing neuronal populations in the brain of the adult sea lamprey by means of in situ hybridization. We also studied the brain of larval sea lampreys to establish whether this prosocial neuropeptide is expressed differentially in two widely different phases of the sea lamprey life cycle. In adult sea lampreys, Ucn3 transcript expression was observed in neurons of the striatum, prethalamus, nucleus of the medial longitudinal fascicle, torus semicircularis, isthmic reticular formation, interpeduncular nucleus, posterior rhombencephalic reticular formation and nucleus of the solitary tract. Interestingly, in larval sea lampreys, only three regions showed Ucn3 expression, namely the prethalamus, the nucleus of the medial longitudinal fascicle and the posterior rhombencephalic reticular formation. A comparison with distributions of Ucn3 in other vertebrates revealed poor conservation of Ucn3 expression during vertebrate evolution. The large qualitative differences in Ucn3 expression observed between larval and adult phases suggest that the maturation of neuroregulatory circuits in the striatum, torus semicircularis and hindbrain chemosensory systems is closely related to profound life-style changes occurring after the transformation from larval to adult life.https://www.mdpi.com/2079-7737/10/10/978urocortin 3in situ hybridizationbrain evolutionstriatumagnathans |
| spellingShingle | Daniel Sobrido-Cameán Ramón Anadón Antón Barreiro-Iglesias Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> Biology urocortin 3 in situ hybridization brain evolution striatum agnathans |
| title | Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> |
| title_full | Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> |
| title_fullStr | Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> |
| title_full_unstemmed | Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> |
| title_short | Expression of Urocortin 3 mRNA in the Central Nervous System of the Sea Lamprey <i>Petromyzon marinus</i> |
| title_sort | expression of urocortin 3 mrna in the central nervous system of the sea lamprey i petromyzon marinus i |
| topic | urocortin 3 in situ hybridization brain evolution striatum agnathans |
| url | https://www.mdpi.com/2079-7737/10/10/978 |
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