NO-sGC Pathway Modulates Ca2+ Release and Muscle Contraction in Zebrafish Skeletal Muscle

NO-sGC Pathway Modulates Ca2+ Release and Muscle Contraction in Zebrafish Skeletal Muscle

Vertebrate skeletal muscle contraction and relaxation is a complex process that depends on Ca2+ ions to promote the interaction of actin and myosin. This process can be modulated by nitric oxide (NO), a gas molecule synthesized endogenously by (nitric oxide synthase) NOS isoforms. At nanomolar conce...

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Bibliographic Details
Main Authors: Zhou Xiyuan, Rainer H. A. Fink, Matias Mosqueira
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Physiology
Subjects:
skeletal muscle
force
calcium transient
nitric oxide
zebrafish
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00607/full

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