Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy
In 2012, a 50 year-old athletic male presented with weakness, pain and unilateral phrenic paralysis, followed by bilateral phrenic paralysis with deep dyspnea. In 2013, the Parsonage-Turner syndrome was diagnosed. When the patient was seen in September 2014 for the first time, he was facing phrenic...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2015-05-01
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| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/381945 |
| _version_ | 1818590893470384128 |
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| author | Jacqueline Le Goaster Patrice Bourée Charles Ifergan Frederic Tangy René Olivier Anne-Lise Haenni |
| author_facet | Jacqueline Le Goaster Patrice Bourée Charles Ifergan Frederic Tangy René Olivier Anne-Lise Haenni |
| author_sort | Jacqueline Le Goaster |
| collection | DOAJ |
| description | In 2012, a 50 year-old athletic male presented with weakness, pain and unilateral phrenic paralysis, followed by bilateral phrenic paralysis with deep dyspnea. In 2013, the Parsonage-Turner syndrome was diagnosed. When the patient was seen in September 2014 for the first time, he was facing phrenic neuromuscular failure, which led to the hypothesis of neurotropic herpes viruses. A control of the global serological anti-Herpes immunity to analyze his antibody (Ab) levels confirmed herpes immune genetic deficiency. An appropriate herpes chemotherapy treatment was proposed. Immediately, a spectacular recovery of the patient was observed, and after a few weeks, the respiratory function tests showed normal values. The hypothesis of the inductive role of viruses of the herpes family in the Parsonage-Turner syndrome was thus substantiated. The patient's immune deficiency covers the HSV2, HHV3, HHV4, HHV5 and HHV6 Ab levels. This led to the control of herpes in the family lineage: indeed, his daughter presented alterations of her serological herpes Ab levels. |
| first_indexed | 2024-12-16T10:03:47Z |
| format | Article |
| id | doaj.art-c732c617877f46a8a66e9e28a94d8677 |
| institution | Directory Open Access Journal |
| issn | 1662-680X |
| language | English |
| last_indexed | 2024-12-16T10:03:47Z |
| publishDate | 2015-05-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj.art-c732c617877f46a8a66e9e28a94d86772022-12-21T22:35:44ZengKarger PublishersCase Reports in Neurology1662-680X2015-05-017211011410.1159/000381945381945Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes TherapyJacqueline Le GoasterPatrice BouréeCharles IferganFrederic TangyRené OlivierAnne-Lise HaenniIn 2012, a 50 year-old athletic male presented with weakness, pain and unilateral phrenic paralysis, followed by bilateral phrenic paralysis with deep dyspnea. In 2013, the Parsonage-Turner syndrome was diagnosed. When the patient was seen in September 2014 for the first time, he was facing phrenic neuromuscular failure, which led to the hypothesis of neurotropic herpes viruses. A control of the global serological anti-Herpes immunity to analyze his antibody (Ab) levels confirmed herpes immune genetic deficiency. An appropriate herpes chemotherapy treatment was proposed. Immediately, a spectacular recovery of the patient was observed, and after a few weeks, the respiratory function tests showed normal values. The hypothesis of the inductive role of viruses of the herpes family in the Parsonage-Turner syndrome was thus substantiated. The patient's immune deficiency covers the HSV2, HHV3, HHV4, HHV5 and HHV6 Ab levels. This led to the control of herpes in the family lineage: indeed, his daughter presented alterations of her serological herpes Ab levels.http://www.karger.com/Article/FullText/381945Appropriate anti-herpes therapyParsonage-Turner syndromeNeuralgic amyotrophyBilateral phrenic paralysisNeurotropic herpes virus occurrences |
| spellingShingle | Jacqueline Le Goaster Patrice Bourée Charles Ifergan Frederic Tangy René Olivier Anne-Lise Haenni Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy Case Reports in Neurology Appropriate anti-herpes therapy Parsonage-Turner syndrome Neuralgic amyotrophy Bilateral phrenic paralysis Neurotropic herpes virus occurrences |
| title | Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy |
| title_full | Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy |
| title_fullStr | Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy |
| title_full_unstemmed | Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy |
| title_short | Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy |
| title_sort | herpes viral origin of the parsonage turner syndrome highlighting of serological immune anti herpes deficiency cured by anti herpes therapy |
| topic | Appropriate anti-herpes therapy Parsonage-Turner syndrome Neuralgic amyotrophy Bilateral phrenic paralysis Neurotropic herpes virus occurrences |
| url | http://www.karger.com/Article/FullText/381945 |
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