Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review
Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma and is characterized by progressive peripheral growth with accompanying central healing. Here, we report a case of multiple KCM. A 53-year-old man presented with multiple erythematous papulonodules on both upper limbs...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-03-01
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| Series: | Dermatologica Sinica |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1027811713000037 |
| _version_ | 1819043121559764992 |
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| author | Chao Shiang Sung Fu Chen Chuang Ji Chen Ho Shang Hong Lin |
| author_facet | Chao Shiang Sung Fu Chen Chuang Ji Chen Ho Shang Hong Lin |
| author_sort | Chao Shiang Sung |
| collection | DOAJ |
| description | Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma and is characterized by progressive peripheral growth with accompanying central healing. Here, we report a case of multiple KCM. A 53-year-old man presented with multiple erythematous papulonodules on both upper limbs and neck for >2 years. His skin lesions enlarged in an annular manner with central residual cribriform scarring that eventually formed confluent plaques (2–8 cm in diameter) with elevated hyperkeratotic borders. Skin biopsy of a developed matured nodule on the right forearm was consistent with that of classical keratoacanthoma. KCM was diagnosed on the basis of clinical and pathological presentation. Low-dose acitretin (0.7 mg/kg/day) was administered and the skin lesions improved significantly within 3 months after the treatment. In this case, we present the clinical and histological features of KCM and discuss the different effective treatment modalities. |
| first_indexed | 2024-12-21T09:51:45Z |
| format | Article |
| id | doaj.art-c738198a32fd416c91af2aba28852870 |
| institution | Directory Open Access Journal |
| issn | 1027-8117 |
| language | English |
| last_indexed | 2024-12-21T09:51:45Z |
| publishDate | 2014-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dermatologica Sinica |
| spelling | doaj.art-c738198a32fd416c91af2aba288528702022-12-21T19:08:10ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172014-03-01321252810.1016/j.dsi.2013.01.002Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature reviewChao Shiang Sung0Fu Chen Chuang1Ji Chen Ho2Shang Hong Lin3Department of Dermatology, Chang Gung Memorial Hospital—Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanDepartment of Dermatology, Chang Gung Memorial Hospital—Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanDepartment of Dermatology, Chang Gung Memorial Hospital—Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanDepartment of Dermatology, Chang Gung Memorial Hospital—Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanKeratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma and is characterized by progressive peripheral growth with accompanying central healing. Here, we report a case of multiple KCM. A 53-year-old man presented with multiple erythematous papulonodules on both upper limbs and neck for >2 years. His skin lesions enlarged in an annular manner with central residual cribriform scarring that eventually formed confluent plaques (2–8 cm in diameter) with elevated hyperkeratotic borders. Skin biopsy of a developed matured nodule on the right forearm was consistent with that of classical keratoacanthoma. KCM was diagnosed on the basis of clinical and pathological presentation. Low-dose acitretin (0.7 mg/kg/day) was administered and the skin lesions improved significantly within 3 months after the treatment. In this case, we present the clinical and histological features of KCM and discuss the different effective treatment modalities.http://www.sciencedirect.com/science/article/pii/S1027811713000037acitretinkeratoacanthomakeratoacanthoma centrifugum marginatum |
| spellingShingle | Chao Shiang Sung Fu Chen Chuang Ji Chen Ho Shang Hong Lin Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review Dermatologica Sinica acitretin keratoacanthoma keratoacanthoma centrifugum marginatum |
| title | Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review |
| title_full | Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review |
| title_fullStr | Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review |
| title_full_unstemmed | Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review |
| title_short | Keratoacanthoma centrifugum marginatum—A rare variant of keratoacanthoma: Case report and literature review |
| title_sort | keratoacanthoma centrifugum marginatum a rare variant of keratoacanthoma case report and literature review |
| topic | acitretin keratoacanthoma keratoacanthoma centrifugum marginatum |
| url | http://www.sciencedirect.com/science/article/pii/S1027811713000037 |
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