The Tie2 signaling pathway in retinal vascular diseases: a novel therapeutic target in the eye

The Tie2 signaling pathway in retinal vascular diseases: a novel therapeutic target in the eye

Abstract Background Retinal vascular diseases such as neovascular age-related macular degeneration, diabetic retinopathy and/or diabetic macular edema, and retinal vein occlusion with macular edema—share several key pathophysiologic aspects including neovascularization, vascular permeability, and in...

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Bibliographic Details
Main Authors: Quan Dong Nguyen, Jeffrey S. Heier, Diana V. Do, Adam C. Mirando, Niranjan B. Pandey, Huan Sheng, Theresa Heah
Format: Article
Language:English
Published: BMC 2020-10-01
Series:International Journal of Retina and Vitreous
Subjects:
Tie2
Integrin
Vascular endothelial grwoth factor
Vascular permeability
AXT107
Online Access:http://link.springer.com/article/10.1186/s40942-020-00250-z

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