4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles

OBJECTIVES/GOALS: Development of gold nanoparticles covalently linked to a photosensitizer for use to enhance radiation therapy. The particles will be thoroughly characterized structurally and mechanistically. The gold particles should enhance radiation activity by closer proximity to the photosensi...

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Main Authors: Samir V Jenkins, Robert J. Griffin
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120003301/type/journal_article
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author Samir V Jenkins
Robert J. Griffin
author_facet Samir V Jenkins
Robert J. Griffin
author_sort Samir V Jenkins
collection DOAJ
description OBJECTIVES/GOALS: Development of gold nanoparticles covalently linked to a photosensitizer for use to enhance radiation therapy. The particles will be thoroughly characterized structurally and mechanistically. The gold particles should enhance radiation activity by closer proximity to the photosensitizer and by increasing particle accumulation in the tumor.
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spelling doaj.art-c73b260fa5b849c89b5345213ad45acd2023-03-10T08:51:36ZengCambridge University PressJournal of Clinical and Translational Science2059-86612020-06-01410710710.1017/cts.2020.3304440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticlesSamir V Jenkins0Robert J. Griffin1University of Arkansas Translational Research InstituteUAMSOBJECTIVES/GOALS: Development of gold nanoparticles covalently linked to a photosensitizer for use to enhance radiation therapy. The particles will be thoroughly characterized structurally and mechanistically. The gold particles should enhance radiation activity by closer proximity to the photosensitizer and by increasing particle accumulation in the tumor.https://www.cambridge.org/core/product/identifier/S2059866120003301/type/journal_article
spellingShingle Samir V Jenkins
Robert J. Griffin
4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
Journal of Clinical and Translational Science
title 4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
title_full 4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
title_fullStr 4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
title_full_unstemmed 4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
title_short 4440 Enhanced radiation therapy using chlorin-e6 conjugated gold nanoparticles
title_sort 4440 enhanced radiation therapy using chlorin e6 conjugated gold nanoparticles
url https://www.cambridge.org/core/product/identifier/S2059866120003301/type/journal_article
work_keys_str_mv AT samirvjenkins 4440enhancedradiationtherapyusingchlorine6conjugatedgoldnanoparticles
AT robertjgriffin 4440enhancedradiationtherapyusingchlorine6conjugatedgoldnanoparticles