Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma
A 22-year-old primigravida who underwent medical abortion at 45 days of amenorrhea was diagnosed to have choriocarcinoma by histopathological examination after dilatation and curettage (D and C) for persistent bleeding per vaginum. Her serum β human chorionic gonadotropin values were less than 1 lak...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | International Journal of Advanced Medical and Health Research |
| Subjects: | |
| Online Access: | http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2015;volume=2;issue=1;spage=65;epage=67;aulast=Papa |
| _version_ | 1818191692271976448 |
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| author | Dasari Papa Haritha Sagili |
| author_facet | Dasari Papa Haritha Sagili |
| author_sort | Dasari Papa |
| collection | DOAJ |
| description | A 22-year-old primigravida who underwent medical abortion at 45 days of amenorrhea was diagnosed to have choriocarcinoma by histopathological examination after dilatation and curettage (D and C) for persistent bleeding per vaginum. Her serum β human chorionic gonadotropin values were less than 1 lakh and she was treated initially with methotrexate monotherapy elsewhere. She needed 10 units of packed cell transfusion for persistent hemorrhage and she was referred to our Institute because of persistent gestational trophoblastic neoplasia and intractable hemorrhage. She needed multiple transfusions and underwent laparotomy and bilateral internal iliac artery ligation with intrauterine packing as she had a severe bout of bleeding resulting in hemorrhagic shock. Post-operatively she was managed with chemotherapy employing EMACO (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine/oncovine) and EMA (etoposide, methotrexate, actinomycin D) and thus her fertility was preserved. |
| first_indexed | 2024-12-12T00:18:39Z |
| format | Article |
| id | doaj.art-c73c2f385d514fcc8826629b9af40862 |
| institution | Directory Open Access Journal |
| issn | 2349-4220 2350-0298 |
| language | English |
| last_indexed | 2024-12-12T00:18:39Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Advanced Medical and Health Research |
| spelling | doaj.art-c73c2f385d514fcc8826629b9af408622022-12-22T00:44:48ZengWolters Kluwer Medknow PublicationsInternational Journal of Advanced Medical and Health Research2349-42202350-02982015-01-0121656710.4103/2349-4220.159165Management of life-threatening uterine hemorrhage in a young patient with choriocarcinomaDasari PapaHaritha SagiliA 22-year-old primigravida who underwent medical abortion at 45 days of amenorrhea was diagnosed to have choriocarcinoma by histopathological examination after dilatation and curettage (D and C) for persistent bleeding per vaginum. Her serum β human chorionic gonadotropin values were less than 1 lakh and she was treated initially with methotrexate monotherapy elsewhere. She needed 10 units of packed cell transfusion for persistent hemorrhage and she was referred to our Institute because of persistent gestational trophoblastic neoplasia and intractable hemorrhage. She needed multiple transfusions and underwent laparotomy and bilateral internal iliac artery ligation with intrauterine packing as she had a severe bout of bleeding resulting in hemorrhagic shock. Post-operatively she was managed with chemotherapy employing EMACO (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine/oncovine) and EMA (etoposide, methotrexate, actinomycin D) and thus her fertility was preserved.http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2015;volume=2;issue=1;spage=65;epage=67;aulast=PapaChoriocarcinomamedical abortionpost-abortal bleeding |
| spellingShingle | Dasari Papa Haritha Sagili Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma International Journal of Advanced Medical and Health Research Choriocarcinoma medical abortion post-abortal bleeding |
| title | Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma |
| title_full | Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma |
| title_fullStr | Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma |
| title_full_unstemmed | Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma |
| title_short | Management of life-threatening uterine hemorrhage in a young patient with choriocarcinoma |
| title_sort | management of life threatening uterine hemorrhage in a young patient with choriocarcinoma |
| topic | Choriocarcinoma medical abortion post-abortal bleeding |
| url | http://www.ijamhrjournal.org/article.asp?issn=2349-4220;year=2015;volume=2;issue=1;spage=65;epage=67;aulast=Papa |
| work_keys_str_mv | AT dasaripapa managementoflifethreateninguterinehemorrhageinayoungpatientwithchoriocarcinoma AT harithasagili managementoflifethreateninguterinehemorrhageinayoungpatientwithchoriocarcinoma |