KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats in vitro

KCNQ Current Contributes to Inspiratory Burst Termination in the Pre-Bötzinger Complex of Neonatal Rats in vitro

The pre-Bötzinger complex (preBötC) of the ventral medulla generates the mammalian inspiratory breathing rhythm. When isolated in explants and deprived of synaptic inhibition, the preBötC continues to generate inspiratory-related rhythm. Mechanisms underlying burst generation have been investigated...

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Bibliographic Details
Main Authors: Ann L. Revill, Alexis Katzell, Christopher A. Del Negro, William K. Milsom, Gregory D. Funk
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
breathing
Kv7
M-current
KCNQ
inspiratory rhythm
respiration
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.626470/full

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