Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults
Abstract Background Studies using functional near-infrared spectroscopy (fNIRS) have shown that dual-task walking leads to greater prefrontal cortex (PFC) activation compared to the single-task walking task. However, evidence on age-related changes in PFC activity patterns is inconsistent. Therefore...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-07-01
|
| Series: | Journal of NeuroEngineering and Rehabilitation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12984-023-01211-x |
| _version_ | 1797784791928537088 |
|---|---|
| author | Chang Yoon Baek Hyeong Dong Kim Dong Yup Yoo Kyoung Yee Kang Jang Woo Lee |
| author_facet | Chang Yoon Baek Hyeong Dong Kim Dong Yup Yoo Kyoung Yee Kang Jang Woo Lee |
| author_sort | Chang Yoon Baek |
| collection | DOAJ |
| description | Abstract Background Studies using functional near-infrared spectroscopy (fNIRS) have shown that dual-task walking leads to greater prefrontal cortex (PFC) activation compared to the single-task walking task. However, evidence on age-related changes in PFC activity patterns is inconsistent. Therefore, this study aimed to explore the changes in the activation patterns of PFC subregions in different activation phases (early and late phases) during both single-task and dual-task walking in both older and younger adults. Methods Overall, 20 older and 15 younger adults performed a walking task with and without a cognitive task. The activity of the PFC subregions in different phases (early and late phases) and task performance (gait and cognitive task) were evaluated using fNIRS and a gait analyzer. Results The gait (slower speed and lower cadence) and cognitive performance (lower total response, correct response and accuracy rate, and higher error rate) of older adults was poorer during the dual task than that of younger adults. Right dorsolateral PFC activity in the early period in older adults was higher than that in younger adults, which declined precipitously during the late period. Conversely, the activity level of the right orbitofrontal cortex in the dual-task for older adults was lower than for younger adults. Conclusions These altered PFC subregion-specific activation patterns in older adults would indicate a decline in dual-task performance with aging. |
| first_indexed | 2024-03-13T00:44:55Z |
| format | Article |
| id | doaj.art-c7444a833f8646f2abe5a7c16b6c4800 |
| institution | Directory Open Access Journal |
| issn | 1743-0003 |
| language | English |
| last_indexed | 2024-03-13T00:44:55Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of NeuroEngineering and Rehabilitation |
| spelling | doaj.art-c7444a833f8646f2abe5a7c16b6c48002023-07-09T11:08:16ZengBMCJournal of NeuroEngineering and Rehabilitation1743-00032023-07-0120111210.1186/s12984-023-01211-xChange in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adultsChang Yoon Baek0Hyeong Dong Kim1Dong Yup Yoo2Kyoung Yee Kang3Jang Woo Lee4Department of Physical Therapy and School of Health and Environmental Science, College of Health Science, Korea UniversityDepartment of Physical Therapy and School of Health and Environmental Science, College of Health Science, Korea UniversityDepartment of Rehabilitation Medicine, National Health Insurance Ilsan HospitalDepartment of Rehabilitation Medicine, National Health Insurance Ilsan HospitalDepartment of Rehabilitation Medicine, National Health Insurance Ilsan HospitalAbstract Background Studies using functional near-infrared spectroscopy (fNIRS) have shown that dual-task walking leads to greater prefrontal cortex (PFC) activation compared to the single-task walking task. However, evidence on age-related changes in PFC activity patterns is inconsistent. Therefore, this study aimed to explore the changes in the activation patterns of PFC subregions in different activation phases (early and late phases) during both single-task and dual-task walking in both older and younger adults. Methods Overall, 20 older and 15 younger adults performed a walking task with and without a cognitive task. The activity of the PFC subregions in different phases (early and late phases) and task performance (gait and cognitive task) were evaluated using fNIRS and a gait analyzer. Results The gait (slower speed and lower cadence) and cognitive performance (lower total response, correct response and accuracy rate, and higher error rate) of older adults was poorer during the dual task than that of younger adults. Right dorsolateral PFC activity in the early period in older adults was higher than that in younger adults, which declined precipitously during the late period. Conversely, the activity level of the right orbitofrontal cortex in the dual-task for older adults was lower than for younger adults. Conclusions These altered PFC subregion-specific activation patterns in older adults would indicate a decline in dual-task performance with aging.https://doi.org/10.1186/s12984-023-01211-xPrefrontal cortexDual-task walkingAgingOlder adult |
| spellingShingle | Chang Yoon Baek Hyeong Dong Kim Dong Yup Yoo Kyoung Yee Kang Jang Woo Lee Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults Journal of NeuroEngineering and Rehabilitation Prefrontal cortex Dual-task walking Aging Older adult |
| title | Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults |
| title_full | Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults |
| title_fullStr | Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults |
| title_full_unstemmed | Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults |
| title_short | Change in activity patterns in the prefrontal cortex in different phases during the dual-task walking in older adults |
| title_sort | change in activity patterns in the prefrontal cortex in different phases during the dual task walking in older adults |
| topic | Prefrontal cortex Dual-task walking Aging Older adult |
| url | https://doi.org/10.1186/s12984-023-01211-x |
| work_keys_str_mv | AT changyoonbaek changeinactivitypatternsintheprefrontalcortexindifferentphasesduringthedualtaskwalkinginolderadults AT hyeongdongkim changeinactivitypatternsintheprefrontalcortexindifferentphasesduringthedualtaskwalkinginolderadults AT dongyupyoo changeinactivitypatternsintheprefrontalcortexindifferentphasesduringthedualtaskwalkinginolderadults AT kyoungyeekang changeinactivitypatternsintheprefrontalcortexindifferentphasesduringthedualtaskwalkinginolderadults AT jangwoolee changeinactivitypatternsintheprefrontalcortexindifferentphasesduringthedualtaskwalkinginolderadults |