Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model, Medicago truncatula

Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model, Medicago truncatula

Abstract Background Third generation sequencing technologies, with sequencing reads in the tens- of kilo-bases, facilitate genome assembly by spanning ambiguous regions and improving continuity. This has been critical for plant genomes, which are difficult to assemble due to high repeat content, gen...

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Bibliographic Details
Main Authors: Karen M. Moll, Peng Zhou, Thiruvarangan Ramaraj, Diego Fajardo, Nicholas P. Devitt, Michael J. Sadowsky, Robert M. Stupar, Peter Tiffin, Jason R. Miller, Nevin D. Young, Kevin A. T. Silverstein, Joann Mudge
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
Genome assembly
Next generation sequencing
BioNano
Dovetail
PacBio
Medicago truncatula
Online Access:http://link.springer.com/article/10.1186/s12864-017-3971-4

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