Erythroid Differentiation Dependent Interaction of VPS13A with XK at the Plasma Membrane of K562 Cells

Erythroid Differentiation Dependent Interaction of VPS13A with XK at the Plasma Membrane of K562 Cells

Mutations of the bridge-like lipid transport protein VPS13A and the lipid scramblase XK result in Chorea Acanthocytosis (ChAc) and McLeod syndrome (MLS), respectively, two similar conditions involving neurodegeneration and deformed erythrocytes (acanthocytes). VPS13A binds XK, suggesting a model in...

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Bibliographic Details
Main Authors: Chase Amos, Peng Xu, Pietro De Camilli
Format: Article
Language:English
Published: SAGE Publishing 2023-12-01
Series:Contact
Online Access:https://doi.org/10.1177/25152564231215133

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