Management of psoriasis in pregnancy – a review of the evidence to date

The onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered. When choosing to treat pregnant women affected by psoriasis with pharmacological therapy, it is important to be awar...

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Bibliographic Details
Main Authors: Clara Ferreira, Alexandra Azevedo, Miguel Nogueira, Tiago Torres
Format: Article
Language:English
Published: BioExcel Publishing Ltd 2020-03-01
Series:Drugs in Context
Subjects:
Online Access:https://www.drugsincontext.com/management-of-psoriasis-in-pregnancy-a-review-of-the-evidence-to-date/
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author Clara Ferreira
Alexandra Azevedo
Miguel Nogueira
Tiago Torres
author_facet Clara Ferreira
Alexandra Azevedo
Miguel Nogueira
Tiago Torres
author_sort Clara Ferreira
collection DOAJ
description The onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered. When choosing to treat pregnant women affected by psoriasis with pharmacological therapy, it is important to be aware of all possible options and their repercussions. Although there are several pharmacological therapies available, pregnancy brings ethical concerns and any pharmacological approach must be well thought out. The data available in humans are limited, and further investigation on this matter is needed. Within biological therapies, certolizumab pegol has recently been identified as a promising approach during pregnancy because it has been shown to have no late active placental transfer and no clear signs of foetal harm. This article aims to review the impact of psoriasis during pregnancy, how the disease can be managed pharmacologically during this period according to the available armamentarium, and the possible effects of the therapeutic options for the mother and the foetus.
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spelling doaj.art-c748a98045764f45b4f838193bb17e432022-12-22T03:15:39ZengBioExcel Publishing LtdDrugs in Context1740-43981740-43982020-03-0191910.7573/dic.2019-11-6Management of psoriasis in pregnancy – a review of the evidence to dateClara FerreiraAlexandra AzevedoMiguel NogueiraTiago TorresThe onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered. When choosing to treat pregnant women affected by psoriasis with pharmacological therapy, it is important to be aware of all possible options and their repercussions. Although there are several pharmacological therapies available, pregnancy brings ethical concerns and any pharmacological approach must be well thought out. The data available in humans are limited, and further investigation on this matter is needed. Within biological therapies, certolizumab pegol has recently been identified as a promising approach during pregnancy because it has been shown to have no late active placental transfer and no clear signs of foetal harm. This article aims to review the impact of psoriasis during pregnancy, how the disease can be managed pharmacologically during this period according to the available armamentarium, and the possible effects of the therapeutic options for the mother and the foetus.https://www.drugsincontext.com/management-of-psoriasis-in-pregnancy-a-review-of-the-evidence-to-date/pregnancypregnancy complicationspsoriasistherapy
spellingShingle Clara Ferreira
Alexandra Azevedo
Miguel Nogueira
Tiago Torres
Management of psoriasis in pregnancy – a review of the evidence to date
Drugs in Context
pregnancy
pregnancy complications
psoriasis
therapy
title Management of psoriasis in pregnancy – a review of the evidence to date
title_full Management of psoriasis in pregnancy – a review of the evidence to date
title_fullStr Management of psoriasis in pregnancy – a review of the evidence to date
title_full_unstemmed Management of psoriasis in pregnancy – a review of the evidence to date
title_short Management of psoriasis in pregnancy – a review of the evidence to date
title_sort management of psoriasis in pregnancy a review of the evidence to date
topic pregnancy
pregnancy complications
psoriasis
therapy
url https://www.drugsincontext.com/management-of-psoriasis-in-pregnancy-a-review-of-the-evidence-to-date/
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AT tiagotorres managementofpsoriasisinpregnancyareviewoftheevidencetodate