High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?

<p>Abstract</p> <p>Results of several recent studies show that high-protein, low-carbohydrate weight loss diets indeed have their benefits. However, agencies such as the American Heart Association (AHA) have some concerns about possible health risks. The purpose of this review is t...

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Main Author: Manninen Anssi H
Format: Article
Language:English
Published: Taylor & Francis Group 2004-05-01
Series:Journal of the International Society of Sports Nutrition
Subjects:
Online Access:http://www.jissn.com/content/1/1/45
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author Manninen Anssi H
author_facet Manninen Anssi H
author_sort Manninen Anssi H
collection DOAJ
description <p>Abstract</p> <p>Results of several recent studies show that high-protein, low-carbohydrate weight loss diets indeed have their benefits. However, agencies such as the American Heart Association (AHA) have some concerns about possible health risks. The purpose of this review is to evaluate the scientific validity of AHA Nutrition Committee's statement on dietary protein and weight reduction (St. Jeor ST et al. <it>Circulation </it>2001;104:1869–1874), which states: "<it>Individuals who follow these </it>[<it>high-protein</it>] <it>diets are risk for ... potential cardiac, renal, bone, and liver abnormalities overall</it>. Simply stated, there is no scientific evidence whatsoever that high-protein intake has adverse effects on liver function. Relative to renal function, there are no data in the scientific literature demonstrating that healthy kidneys are damaged by the increased demands of protein consumed in quantities 2–3 times above the Recommended Dietary Allowance (RDA). In contrast with the earlier hypothesis that high-protein intake promotes osteoporosis, some epidemiological studies found a positive association between protein intake and bone mineral density. Further, recent studies studies suggest, at least in the short term, that RDA for protein (0.8 g/kg) does not support normal calcium homeostasis. Finally, a negative correlation has been shown between protein intake and systolic and diastolic blood pressures in several epidemiological surveys. In conclusion, there is little if any scientific evidence supporting above mentioned statement. Certainly, such public warnings should be based on a thorough analysis of the scientific literature, not unsubstantiated fears and misrepresentations. For individuals with normal renal function, the risks are minimal and must be balanced against the real and established risk of continued obesity.</p>
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spelling doaj.art-c74b1518063347b5af7726f0392a0ade2022-12-22T01:19:37ZengTaylor & Francis GroupJournal of the International Society of Sports Nutrition1550-27832004-05-0111455110.1186/1550-2783-1-1-45High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?Manninen Anssi H<p>Abstract</p> <p>Results of several recent studies show that high-protein, low-carbohydrate weight loss diets indeed have their benefits. However, agencies such as the American Heart Association (AHA) have some concerns about possible health risks. The purpose of this review is to evaluate the scientific validity of AHA Nutrition Committee's statement on dietary protein and weight reduction (St. Jeor ST et al. <it>Circulation </it>2001;104:1869–1874), which states: "<it>Individuals who follow these </it>[<it>high-protein</it>] <it>diets are risk for ... potential cardiac, renal, bone, and liver abnormalities overall</it>. Simply stated, there is no scientific evidence whatsoever that high-protein intake has adverse effects on liver function. Relative to renal function, there are no data in the scientific literature demonstrating that healthy kidneys are damaged by the increased demands of protein consumed in quantities 2–3 times above the Recommended Dietary Allowance (RDA). In contrast with the earlier hypothesis that high-protein intake promotes osteoporosis, some epidemiological studies found a positive association between protein intake and bone mineral density. Further, recent studies studies suggest, at least in the short term, that RDA for protein (0.8 g/kg) does not support normal calcium homeostasis. Finally, a negative correlation has been shown between protein intake and systolic and diastolic blood pressures in several epidemiological surveys. In conclusion, there is little if any scientific evidence supporting above mentioned statement. Certainly, such public warnings should be based on a thorough analysis of the scientific literature, not unsubstantiated fears and misrepresentations. For individuals with normal renal function, the risks are minimal and must be balanced against the real and established risk of continued obesity.</p>http://www.jissn.com/content/1/1/45high-protein dietsadverse effectsAmerican Heart Association
spellingShingle Manninen Anssi H
High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
Journal of the International Society of Sports Nutrition
high-protein diets
adverse effects
American Heart Association
title High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
title_full High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
title_fullStr High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
title_full_unstemmed High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
title_short High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence?
title_sort high protein weight loss diets and purported adverse effects where is the evidence
topic high-protein diets
adverse effects
American Heart Association
url http://www.jissn.com/content/1/1/45
work_keys_str_mv AT manninenanssih highproteinweightlossdietsandpurportedadverseeffectswhereistheevidence