Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract
The effect of elicitation with jasmonic acids (JA) and yeast extract (YE) on the production of phenolic compounds as well as the antioxidant and anti-inflammatory properties of phenolic extracts of lovage was evaluated. The analysis of phenolic compounds carried out with the UPLC-MS technique indica...
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MDPI AG
2019-04-01
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| Series: | Molecules |
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| author | Urszula Złotek Urszula Szymanowska Łukasz Pecio Solomiia Kozachok Anna Jakubczyk |
| author_facet | Urszula Złotek Urszula Szymanowska Łukasz Pecio Solomiia Kozachok Anna Jakubczyk |
| author_sort | Urszula Złotek |
| collection | DOAJ |
| description | The effect of elicitation with jasmonic acids (JA) and yeast extract (YE) on the production of phenolic compounds as well as the antioxidant and anti-inflammatory properties of phenolic extracts of lovage was evaluated. The analysis of phenolic compounds carried out with the UPLC-MS technique indicated that rutin was the dominant flavonoid, while 5-caffeoylquinic acid was the main component in the phenolic acid fraction in the lovage leaves. The application of 10 µM JA increased the content of most of the identified phenolic compounds. The highest antioxidant activities estimated as free radical scavenging activity against ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and reducing power were determined for the sample elicited with 10 µM JA, while this value determined as iron chelating ability was the highest for the 0.1% YE-elicited lovage. The 0.1% and 1% YE elicitation also caused significant elevation of the lipoxygenase (LOX) inhibition ability, while all the concentrations of the tested elicitors significantly improved the ability to inhibit cyclooxygenase 2 (COX2) (best results were detected for the 10 µM JA and 0.1% YE2 sample). Thus, 0.1% yeast extract and 10 µM jasmonic acid proved to be most effective in elevation of the biological activity of lovage. |
| first_indexed | 2024-12-14T13:02:46Z |
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| id | doaj.art-c74dc482f58a4104801650227818f146 |
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| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-14T13:02:46Z |
| publishDate | 2019-04-01 |
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| series | Molecules |
| spelling | doaj.art-c74dc482f58a4104801650227818f1462022-12-21T23:00:23ZengMDPI AGMolecules1420-30492019-04-01247144110.3390/molecules24071441molecules24071441Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast ExtractUrszula Złotek0Urszula Szymanowska1Łukasz Pecio2Solomiia Kozachok3Anna Jakubczyk4Department of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, PolandDepartment of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, PolandDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation—State Research Institute, Czartoryskich 8, 24-100 Puławy, PolandDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation—State Research Institute, Czartoryskich 8, 24-100 Puławy, PolandDepartment of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, PolandThe effect of elicitation with jasmonic acids (JA) and yeast extract (YE) on the production of phenolic compounds as well as the antioxidant and anti-inflammatory properties of phenolic extracts of lovage was evaluated. The analysis of phenolic compounds carried out with the UPLC-MS technique indicated that rutin was the dominant flavonoid, while 5-caffeoylquinic acid was the main component in the phenolic acid fraction in the lovage leaves. The application of 10 µM JA increased the content of most of the identified phenolic compounds. The highest antioxidant activities estimated as free radical scavenging activity against ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and reducing power were determined for the sample elicited with 10 µM JA, while this value determined as iron chelating ability was the highest for the 0.1% YE-elicited lovage. The 0.1% and 1% YE elicitation also caused significant elevation of the lipoxygenase (LOX) inhibition ability, while all the concentrations of the tested elicitors significantly improved the ability to inhibit cyclooxygenase 2 (COX2) (best results were detected for the 10 µM JA and 0.1% YE2 sample). Thus, 0.1% yeast extract and 10 µM jasmonic acid proved to be most effective in elevation of the biological activity of lovage.https://www.mdpi.com/1420-3049/24/7/1441lovageelicitationphenolic compoundsantioxidant activitiesanti-inflammatory properties |
| spellingShingle | Urszula Złotek Urszula Szymanowska Łukasz Pecio Solomiia Kozachok Anna Jakubczyk Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract Molecules lovage elicitation phenolic compounds antioxidant activities anti-inflammatory properties |
| title | Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract |
| title_full | Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract |
| title_fullStr | Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract |
| title_full_unstemmed | Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract |
| title_short | Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves <em>Levisticum officinale</em> Koch Elicited with Jasmonic Acid and Yeast Extract |
| title_sort | antioxidative and potentially anti inflammatory activity of phenolics from lovage leaves em levisticum officinale em koch elicited with jasmonic acid and yeast extract |
| topic | lovage elicitation phenolic compounds antioxidant activities anti-inflammatory properties |
| url | https://www.mdpi.com/1420-3049/24/7/1441 |
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