Pregnancy-associated plasma protein-aa regulates endoplasmic reticulum–mitochondria associations

Pregnancy-associated plasma protein-aa regulates endoplasmic reticulum–mitochondria associations

Endoplasmic reticulum (ER) and mitochondria form close physical associations to facilitate calcium transfer, thereby regulating mitochondrial function. Neurons with high metabolic demands, such as sensory hair cells, are especially dependent on precisely regulated ER–mitochondria associations. We pr...

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Bibliographic Details
Main Authors: Mroj Alassaf, Mary C Halloran
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
autophagy
IGF signaling
ER stress
hair cell
neurodegeneration
zebrafish
Online Access:https://elifesciences.org/articles/59687

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