A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report
Abstract Background The pharmacological treatment for autism spectrum disorders is often poorly tolerated and has traditionally targeted associated conditions, with limited benefit for the core social deficits. We describe the novel use of a cannabidiol-based extract that incidentally improved core...
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| Format: | Article |
| Language: | English |
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BMC
2020-09-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13256-020-02478-7 |
| _version_ | 1818342034448056320 |
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| author | Juliana Andrea Ponton Kim Smyth Elias Soumbasis Sergio Andres Llanos Mark Lewis Wilhelm August Meerholz Robert Lawrence Tanguay |
| author_facet | Juliana Andrea Ponton Kim Smyth Elias Soumbasis Sergio Andres Llanos Mark Lewis Wilhelm August Meerholz Robert Lawrence Tanguay |
| author_sort | Juliana Andrea Ponton |
| collection | DOAJ |
| description | Abstract Background The pharmacological treatment for autism spectrum disorders is often poorly tolerated and has traditionally targeted associated conditions, with limited benefit for the core social deficits. We describe the novel use of a cannabidiol-based extract that incidentally improved core social deficits and overall functioning in a patient with autism spectrum disorder, at a lower dose than has been previously reported in autism spectrum disorder. Case presentation The parents of a 15-year-old boy, of South African descent, with autism spectrum disorder, selective mutism, anxiety, and controlled epilepsy, consulted a medical cannabis physician to trial cannabis extract to replace seizure medications. Incidentally, at a very low cannabidiol-based extract dose, he experienced unanticipated positive effects on behavioral symptoms and core social deficits. Conclusion This case report provides evidence that a lower than previously reported dose of a phytocannabinoid in the form of a cannabidiol-based extract may be capable of aiding in autism spectrum disorder-related behavioral symptoms, core social communication abilities, and comorbid anxiety, sleep difficulties, and weight control. Further research is needed to elucidate the clinical role and underlying biological mechanisms of action of cannabidiol-based extract in patients with autism spectrum disorder. |
| first_indexed | 2024-12-13T16:08:16Z |
| format | Article |
| id | doaj.art-c75a0f248c004b51bfebfdb45773de22 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-13T16:08:16Z |
| publishDate | 2020-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-c75a0f248c004b51bfebfdb45773de222022-12-21T23:39:00ZengBMCJournal of Medical Case Reports1752-19472020-09-011411710.1186/s13256-020-02478-7A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case reportJuliana Andrea Ponton0Kim Smyth1Elias Soumbasis2Sergio Andres Llanos3Mark Lewis4Wilhelm August Meerholz5Robert Lawrence Tanguay6Caleo HealthAlberta Children’s HospitalCaleo HealthCaleo HealthCaleo HealthCaleo HealthCaleo HealthAbstract Background The pharmacological treatment for autism spectrum disorders is often poorly tolerated and has traditionally targeted associated conditions, with limited benefit for the core social deficits. We describe the novel use of a cannabidiol-based extract that incidentally improved core social deficits and overall functioning in a patient with autism spectrum disorder, at a lower dose than has been previously reported in autism spectrum disorder. Case presentation The parents of a 15-year-old boy, of South African descent, with autism spectrum disorder, selective mutism, anxiety, and controlled epilepsy, consulted a medical cannabis physician to trial cannabis extract to replace seizure medications. Incidentally, at a very low cannabidiol-based extract dose, he experienced unanticipated positive effects on behavioral symptoms and core social deficits. Conclusion This case report provides evidence that a lower than previously reported dose of a phytocannabinoid in the form of a cannabidiol-based extract may be capable of aiding in autism spectrum disorder-related behavioral symptoms, core social communication abilities, and comorbid anxiety, sleep difficulties, and weight control. Further research is needed to elucidate the clinical role and underlying biological mechanisms of action of cannabidiol-based extract in patients with autism spectrum disorder.http://link.springer.com/article/10.1186/s13256-020-02478-7AutismCannabidiol extractPhytocannabinoidsComplementary treatment |
| spellingShingle | Juliana Andrea Ponton Kim Smyth Elias Soumbasis Sergio Andres Llanos Mark Lewis Wilhelm August Meerholz Robert Lawrence Tanguay A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report Journal of Medical Case Reports Autism Cannabidiol extract Phytocannabinoids Complementary treatment |
| title | A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report |
| title_full | A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report |
| title_fullStr | A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report |
| title_full_unstemmed | A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report |
| title_short | A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report |
| title_sort | pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy a case report |
| topic | Autism Cannabidiol extract Phytocannabinoids Complementary treatment |
| url | http://link.springer.com/article/10.1186/s13256-020-02478-7 |
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