JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis

JUNB mediates oxaliplatin resistance via the MAPK signaling pathway in gastric cancer by chromatin accessibility and transcriptomic analysis

Currently, platinum-containing regimens are the most commonly used regimens for advanced gastric cancer patients, and chemotherapy resistance is one of the main reasons for treatment failure. Thus, it is important to reveal the mechanism of oxaliplatin resistance and to seek effective intervention s...

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Bibliographic Details
Main Authors: Li Suyao, Wei Yichou, Sun Xun, Liu Mengling, Zhu Mengxuan, Yuan Yitao, Zhang Jiayu, Dong Yu, Hu Keshu, Ma Sining, Zhang Xiuping, Xu Bei, Jiang Hesheng, Gan Lu, Liu Tianshu
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-06-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
gastric cancer
JUNB
ATAC-seq
oxaliplatin resistance
MAPK signaling pathway
chromatin accessibility
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023119

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