Advances in the regulatory mechanisms of mTOR in necroptosis

Advances in the regulatory mechanisms of mTOR in necroptosis

The mammalian target of rapamycin (mTOR), an evolutionarily highly conserved serine/threonine protein kinase, plays a prominent role in controlling gene expression, metabolism, and cell death. Programmed cell death (PCD) is indispensable for maintaining homeostasis by removing senescent, defective,...

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Bibliographic Details
Main Authors: Yawen Xie, Guoyu Zhao, Xianli Lei, Na Cui, Hao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
mTOR
necroptosis
autophagy
RIPK
ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297408/full

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