Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature
Patients with COVID-19 often experience significant cardiovascular complications, including heart failure, myocarditis, and acute coronary syndrome. We present the case of a male patient with severe COVID-19 pneumonia, complicated with inferior ST-segment elevation myocardial infarction (STEMI), whi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/12/2/214 |
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| author | Angeliki Papageorgiou Athanasios Moulias Athanasios Papageorgiou Theodoros Karampitsakos Anastasios Apostolos Grigorios Tsigkas Periklis Davlouros |
| author_facet | Angeliki Papageorgiou Athanasios Moulias Athanasios Papageorgiou Theodoros Karampitsakos Anastasios Apostolos Grigorios Tsigkas Periklis Davlouros |
| author_sort | Angeliki Papageorgiou |
| collection | DOAJ |
| description | Patients with COVID-19 often experience significant cardiovascular complications, including heart failure, myocarditis, and acute coronary syndrome. We present the case of a male patient with severe COVID-19 pneumonia, complicated with inferior ST-segment elevation myocardial infarction (STEMI), which was attributed to spontaneous coronary artery dissection (SCAD). We also make a review of the literature on case reports of patients with COVID-19 and acute myocardial infarction due to SCAD. Through these clinical cases, a potential correlation between SCAD and COVID-19 infection is implied. Endothelial dysfunction, thrombotic complications, and disturbance of the vascular tone are established COVID-19 sequelae, triggered either by direct viral injury or mediated by the cytokines’ storm. These abnormalities in the coronary vasculature and the vasa vasorum could result in SCAD. Moreover, disturbances of the vascular tone can cause coronary vasospasm, a reported precipitant of SCAD. Thus, SCAD should be considered in COVID-19 patients with acute coronary syndrome (ACS), and in the case of STEMI, an early angiographic evaluation, if feasible, should be performed rather than thrombolysis to avoid potential adverse events of the latter in the setting of SCAD. |
| first_indexed | 2024-03-08T10:51:45Z |
| format | Article |
| id | doaj.art-c76afbe0938445daa4bc563daf681a4d |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-08T10:51:45Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-c76afbe0938445daa4bc563daf681a4d2024-01-26T16:46:55ZengMDPI AGHealthcare2227-90322024-01-0112221410.3390/healthcare12020214Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the LiteratureAngeliki Papageorgiou0Athanasios Moulias1Athanasios Papageorgiou2Theodoros Karampitsakos3Anastasios Apostolos4Grigorios Tsigkas5Periklis Davlouros6Cardiology Department, University Hospital of Patras, 26504 Patras, GreeceCardiology Department, University Hospital of Patras, 26504 Patras, GreeceCardiology Department, University Hospital of Patras, 26504 Patras, GreeceUbben Center and Laboratory for Pulmonary Fibrosis Research, University of South Florida, Tampa, FL 33620, USAFirst Department of Cardiology, Hippokration General Hospital, 11527 Athens, GreeceCardiology Department, University Hospital of Patras, 26504 Patras, GreeceCardiology Department, University Hospital of Patras, 26504 Patras, GreecePatients with COVID-19 often experience significant cardiovascular complications, including heart failure, myocarditis, and acute coronary syndrome. We present the case of a male patient with severe COVID-19 pneumonia, complicated with inferior ST-segment elevation myocardial infarction (STEMI), which was attributed to spontaneous coronary artery dissection (SCAD). We also make a review of the literature on case reports of patients with COVID-19 and acute myocardial infarction due to SCAD. Through these clinical cases, a potential correlation between SCAD and COVID-19 infection is implied. Endothelial dysfunction, thrombotic complications, and disturbance of the vascular tone are established COVID-19 sequelae, triggered either by direct viral injury or mediated by the cytokines’ storm. These abnormalities in the coronary vasculature and the vasa vasorum could result in SCAD. Moreover, disturbances of the vascular tone can cause coronary vasospasm, a reported precipitant of SCAD. Thus, SCAD should be considered in COVID-19 patients with acute coronary syndrome (ACS), and in the case of STEMI, an early angiographic evaluation, if feasible, should be performed rather than thrombolysis to avoid potential adverse events of the latter in the setting of SCAD.https://www.mdpi.com/2227-9032/12/2/214spontaneous coronary artery dissectionnon-atherosclerotic acute myocardial infarctionCOVID-19 cardiac complicationscauses of STEMI in COVID-19 patients |
| spellingShingle | Angeliki Papageorgiou Athanasios Moulias Athanasios Papageorgiou Theodoros Karampitsakos Anastasios Apostolos Grigorios Tsigkas Periklis Davlouros Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature Healthcare spontaneous coronary artery dissection non-atherosclerotic acute myocardial infarction COVID-19 cardiac complications causes of STEMI in COVID-19 patients |
| title | Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature |
| title_full | Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature |
| title_fullStr | Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature |
| title_full_unstemmed | Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature |
| title_short | Spontaneous Coronary Artery Dissection as a Cause of Acute Myocardial Infarction in COVID-19 Patients: A Case Report and Review of the Literature |
| title_sort | spontaneous coronary artery dissection as a cause of acute myocardial infarction in covid 19 patients a case report and review of the literature |
| topic | spontaneous coronary artery dissection non-atherosclerotic acute myocardial infarction COVID-19 cardiac complications causes of STEMI in COVID-19 patients |
| url | https://www.mdpi.com/2227-9032/12/2/214 |
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