The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial

Introduction: Cesarean section is one of the most common surgeries in midwifery. Due to the lack of a coordinated approach for antibiotic injection before cesarean section and not knowing the advantages and disadvantages of antibiotic injection time on mother and fetus, therefore, this study was per...

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Main Authors: Zeinab Shahbazzadeh, Mozhdeh Navinezhad, Masoumeh Sharifzadeh, Parastoo Amiri, Mitra Eftekhar Yazdi
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2021-07-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_18570_2e4c0251507d673bcbc7a252eb36efa2.pdf
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author Zeinab Shahbazzadeh
Mozhdeh Navinezhad
Masoumeh Sharifzadeh
Parastoo Amiri
Mitra Eftekhar Yazdi
author_facet Zeinab Shahbazzadeh
Mozhdeh Navinezhad
Masoumeh Sharifzadeh
Parastoo Amiri
Mitra Eftekhar Yazdi
author_sort Zeinab Shahbazzadeh
collection DOAJ
description Introduction: Cesarean section is one of the most common surgeries in midwifery. Due to the lack of a coordinated approach for antibiotic injection before cesarean section and not knowing the advantages and disadvantages of antibiotic injection time on mother and fetus, therefore, this study was performed with aim to compare the effectiveness of prophylactic antibiotics prescribing before cesarean section with prescribing after umbilical cord clamping to prevent infection after cesarean section. Methods: This triple-blind randomized clinical trial study was performed on 150 women with cesarean delivery in Shahidan Mobini Hospital of Sabzevar in 2019. In the intervention group, antibiotic was administered after umbilical cord clamping and in the control group, antibiotic was administered before cesarean section incision. Symptoms of infection were assessed using the checklist on the 3rd, 10th, and 14th days. Data were analyzed by SPSS software (version 19) and Chi-square, Exact Fisher and Mann-Whitney tests. p < 0.05 was considered statistically significant. Results: On the 3rd day after surgery, none of the patients in the two groups had infection. On the 10th day, 1 patient (1.3%) in the intervention group and 3 (4%) in the control group developed symptoms of infection (p = 0.31). On the 14th day after surgery, 1 patient (1.3%) in the control group and 5 (6.7%) in the intervention group had symptoms of infection (p = 0.10). The difference of infection on the 10th and 14th days was not statistically significant in the two groups. Conclusion: Antibiotic injection after umbilical cord clamping and one hour before surgery does not differ in the rate of postoperative infection.
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spelling doaj.art-c76b378d81e34dfd83bdcc59a5f2193a2022-12-22T03:58:00ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632021-07-01245404710.22038/ijogi.2021.1857018570The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trialZeinab Shahbazzadeh0Mozhdeh Navinezhad1Masoumeh Sharifzadeh2Parastoo Amiri3Mitra Eftekhar Yazdi4General Practitioner, Student Research Committee, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.M.Sc. of Midwifery, School of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran.M.Sc. of Counseling in Midwifery, School of Nursing and Midwifery, Sabzevar University of Medical Sciences, Sabzevar, Iran.Community Medicine Specialist, Elderly Health Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.Assistant Professor, Department of Perinatology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.Introduction: Cesarean section is one of the most common surgeries in midwifery. Due to the lack of a coordinated approach for antibiotic injection before cesarean section and not knowing the advantages and disadvantages of antibiotic injection time on mother and fetus, therefore, this study was performed with aim to compare the effectiveness of prophylactic antibiotics prescribing before cesarean section with prescribing after umbilical cord clamping to prevent infection after cesarean section. Methods: This triple-blind randomized clinical trial study was performed on 150 women with cesarean delivery in Shahidan Mobini Hospital of Sabzevar in 2019. In the intervention group, antibiotic was administered after umbilical cord clamping and in the control group, antibiotic was administered before cesarean section incision. Symptoms of infection were assessed using the checklist on the 3rd, 10th, and 14th days. Data were analyzed by SPSS software (version 19) and Chi-square, Exact Fisher and Mann-Whitney tests. p < 0.05 was considered statistically significant. Results: On the 3rd day after surgery, none of the patients in the two groups had infection. On the 10th day, 1 patient (1.3%) in the intervention group and 3 (4%) in the control group developed symptoms of infection (p = 0.31). On the 14th day after surgery, 1 patient (1.3%) in the control group and 5 (6.7%) in the intervention group had symptoms of infection (p = 0.10). The difference of infection on the 10th and 14th days was not statistically significant in the two groups. Conclusion: Antibiotic injection after umbilical cord clamping and one hour before surgery does not differ in the rate of postoperative infection.https://ijogi.mums.ac.ir/article_18570_2e4c0251507d673bcbc7a252eb36efa2.pdfantibioticscesarean sectionsurgical wound infection
spellingShingle Zeinab Shahbazzadeh
Mozhdeh Navinezhad
Masoumeh Sharifzadeh
Parastoo Amiri
Mitra Eftekhar Yazdi
The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
antibiotics
cesarean section
surgical wound infection
title The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
title_full The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
title_fullStr The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
title_full_unstemmed The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
title_short The effectiveness of prophylactic antibiotic prescribing (preventive) before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section: a triple-blind randomized clinical trial
title_sort effectiveness of prophylactic antibiotic prescribing preventive before cesarean section and prescribing after umbilical cord clamping in the infection after cesarean section a triple blind randomized clinical trial
topic antibiotics
cesarean section
surgical wound infection
url https://ijogi.mums.ac.ir/article_18570_2e4c0251507d673bcbc7a252eb36efa2.pdf
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