Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.

Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.

Preeclampsia is one of the most serious complications of pregnancy. Currently there are no medical treatments. Given placental oxidative stress may be an early trigger in the pathogenesis of preeclampsia, therapies that enhance antioxidant pathways have been proposed as treatments. Melatonin is a di...

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Bibliografische gegevens
Hoofdauteurs:	Natalie J Hannan, Natalie K Binder, Sally Beard, Tuong-Vi Nguyen, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	Public Library of Science (PLoS) 2018-01-01
Reeks:	PLoS ONE
Online toegang:	http://europepmc.org/articles/PMC5894956?pdf=render

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