Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.

Preeclampsia is one of the most serious complications of pregnancy. Currently there are no medical treatments. Given placental oxidative stress may be an early trigger in the pathogenesis of preeclampsia, therapies that enhance antioxidant pathways have been proposed as treatments. Melatonin is a di...

詳細記述

書誌詳細
主要な著者: Natalie J Hannan, Natalie K Binder, Sally Beard, Tuong-Vi Nguyen, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2018-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC5894956?pdf=render