OC_Finder: Osteoclast Segmentation, Counting, and Classification Using Watershed and Deep Learning
Osteoclasts are multinucleated cells that exclusively resorb bone matrix proteins and minerals on the bone surface. They differentiate from monocyte/macrophage lineage cells in the presence of osteoclastogenic cytokines such as the receptor activator of nuclear factor-κB ligand (RANKL) and are stain...
Main Authors: | Xiao Wang, Mizuho Kittaka, Yilin He, Yiwei Zhang, Yasuyoshi Ueki, Daisuke Kihara |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-03-01
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Series: | Frontiers in Bioinformatics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2022.819570/full |
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