Polydatin alleviates hyperuricemia combined with gouty arthritis in mice via regulating urate transporters, NLRP3 inflammasome and NF-κB pathway

Polydatin alleviates hyperuricemia combined with gouty arthritis in mice via regulating urate transporters, NLRP3 inflammasome and NF-κB pathway

Gout is a metabolic disease that seriously affects people's health. Polydatin, a stilbene compound isolated from Polygonum cuspidatum, has attracted much attention because of its rich biological activity and high safety. This study aimed to investigate the therapeutic effect and mechanism of po...

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Bibliographic Details
Main Authors: Wenjing Xu, Yufeng Chen, Fenfen Li, Xiaoxi Zhang, Cantao Li, Chenxi Wu, Yan Huang, Daozong Xia
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Functional Foods
Subjects:
Gout
Hyperuricemia
Polydatin
Urate transporters
NLRP3 inflammasome
NF-κB pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623001822

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