Strategies to develop vaccines of pediatric interest
Introduction: The success of the vaccines available on the market has significantly increased interest in vaccine development. Areas covered: The main aim of this paper is to discuss the most important vaccines of pediatric interest that are currently being developed. New pneumococcal vaccines and v...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-02-01
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| Series: | Expert Review of Vaccines |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/14760584.2017.1237875 |
| _version_ | 1797680449386971136 |
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| author | Susanna Esposito Nicola Principi |
| author_facet | Susanna Esposito Nicola Principi |
| author_sort | Susanna Esposito |
| collection | DOAJ |
| description | Introduction: The success of the vaccines available on the market has significantly increased interest in vaccine development. Areas covered: The main aim of this paper is to discuss the most important vaccines of pediatric interest that are currently being developed. New pneumococcal vaccines and vaccines against group B Streptococcus, Staphylococcus aureus and respiratory syncytial virus are analyzed in detail. Expert commentary: Advances in understanding human immunology, including human monoclonal antibody identification, sequencing technology, and the ability to solve atomic level structures of vaccine targets have provided tools to guide the rational design of future vaccines. It is likely that some of these vaccines will reach the market in the future and will thus partially contribute to the prevention of very severe diseases that significantly affect the morbidity and mortality of children. However, further studies in animals and several clinical trials in children must be performed before new vaccines become licensed. |
| first_indexed | 2024-03-11T23:30:12Z |
| format | Article |
| id | doaj.art-c77dbafb0cd4459e9df6345a70271500 |
| institution | Directory Open Access Journal |
| issn | 1476-0584 1744-8395 |
| language | English |
| last_indexed | 2024-03-11T23:30:12Z |
| publishDate | 2017-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Expert Review of Vaccines |
| spelling | doaj.art-c77dbafb0cd4459e9df6345a702715002023-09-20T10:18:01ZengTaylor & Francis GroupExpert Review of Vaccines1476-05841744-83952017-02-0116217518610.1080/14760584.2017.12378751237875Strategies to develop vaccines of pediatric interestSusanna Esposito0Nicola Principi1Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoUniversità degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoIntroduction: The success of the vaccines available on the market has significantly increased interest in vaccine development. Areas covered: The main aim of this paper is to discuss the most important vaccines of pediatric interest that are currently being developed. New pneumococcal vaccines and vaccines against group B Streptococcus, Staphylococcus aureus and respiratory syncytial virus are analyzed in detail. Expert commentary: Advances in understanding human immunology, including human monoclonal antibody identification, sequencing technology, and the ability to solve atomic level structures of vaccine targets have provided tools to guide the rational design of future vaccines. It is likely that some of these vaccines will reach the market in the future and will thus partially contribute to the prevention of very severe diseases that significantly affect the morbidity and mortality of children. However, further studies in animals and several clinical trials in children must be performed before new vaccines become licensed.http://dx.doi.org/10.1080/14760584.2017.1237875childrengroup b streptococcuspreventionrsvstaphylococcus aureusstreptococcus pneumoniaevaccine |
| spellingShingle | Susanna Esposito Nicola Principi Strategies to develop vaccines of pediatric interest Expert Review of Vaccines children group b streptococcus prevention rsv staphylococcus aureus streptococcus pneumoniae vaccine |
| title | Strategies to develop vaccines of pediatric interest |
| title_full | Strategies to develop vaccines of pediatric interest |
| title_fullStr | Strategies to develop vaccines of pediatric interest |
| title_full_unstemmed | Strategies to develop vaccines of pediatric interest |
| title_short | Strategies to develop vaccines of pediatric interest |
| title_sort | strategies to develop vaccines of pediatric interest |
| topic | children group b streptococcus prevention rsv staphylococcus aureus streptococcus pneumoniae vaccine |
| url | http://dx.doi.org/10.1080/14760584.2017.1237875 |
| work_keys_str_mv | AT susannaesposito strategiestodevelopvaccinesofpediatricinterest AT nicolaprincipi strategiestodevelopvaccinesofpediatricinterest |