Sedative efficacy of nitrous oxide combined with midazolam in extraction of impacted supernumerary teeth in children
Objective To study the sedative efficacy and safety of nitrous oxide (N2O ) inhalation combined with oral midazolam in children with impacted supernumerary teeth for extraction under sedation and to provide a reference for the selection of anesthetic methods for children undergoing impacted teeth...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2019-05-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2019.05.006 |
| Summary: | Objective To study the sedative efficacy and safety of nitrous oxide (N2O ) inhalation combined with
oral midazolam in children with impacted supernumerary teeth for extraction under sedation and to provide a reference
for the selection of anesthetic methods for children undergoing impacted teeth extraction. Methods Sixty patients aged
5 ⁃ 10 years with maxillary impacted supernumerary teeth were randomly divided into three groups, with 20 in each
group, as follows: the N2O group: N2O inhalation sedation before the operation; the midazolam group: oral midazolam se⁃
dation before the operation; the combination group: N2O inhalation combined with oral midazolam sedation before the
operation. Sedation was performed before extraction under local anesthesia. The Ramsay sedation effect, Houpt behavior⁃
al score and incidence of adverse reactions were evaluated after the operation. Results The Ramsay sedation scale
score was significantly higher in the combination group (2.75 ± 0.55) than in the N2O group (2.30 ± 0.47) and the mid⁃
azolam group (2.40 ± 0.50) (P < 0.05). Similarly, the Houpt behavioral rating scale score was significantly higher in the
combination group (5.25 ± 0.64) than in the N2O group (4.70 ± 0.73) and the midazolam group (4.80 ± 0.69) (P < 0.05).
The adverse reaction rate was lower in the combination group (5%) than in the N2O group (10%) and the midazolam group (10% ), but the difference was not significant (χ2＝0.436, P＝0.804). Conclusion N2O inhalation combined
with oral midazolam sedation in the extraction of impacted supernumerary teeth in children can significantly improve
the sedative and therapeutic efficacy and is a safe and effective sedation method. |
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| ISSN: | 2096-1456 2096-1456 |