The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2024-01-01
|
Series: | Journal of Pharmacy and Bioallied Sciences |
Subjects: | |
Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagde |
_version_ | 1827293113504235520 |
---|---|
author | Hiroj S Bagde Mohammad K Alam Yazan Eid Muteb Almohammed Sufyan Mohammed Mukhlef Almaqawid Abdulelah Waheed Noman Alanazi Fawaz Talal F. Alanazi Mohammed G Sghaireen |
author_facet | Hiroj S Bagde Mohammad K Alam Yazan Eid Muteb Almohammed Sufyan Mohammed Mukhlef Almaqawid Abdulelah Waheed Noman Alanazi Fawaz Talal F. Alanazi Mohammed G Sghaireen |
author_sort | Hiroj S Bagde |
collection | DOAJ |
description | Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to bone grafting in ARP to enhance bone regeneration. Materials and Methods: A total of 60 patients requiring tooth extraction and ARP were included in this randomized controlled trial. Patients were divided into two groups: Group A received bone grafting alone, while Group B received bone grafting with PRP. Clinical and radiographic assessments were performed at baseline and 6-month postsurgery. Bone density and height were measured using arbitrary values. Results: At the 6-month follow-up, Group B demonstrated a statistically significant increase in bone density (P < 0.05) and bone height (P < 0.05) compared to Group A. The arbitrary values for bone density in Group B increased by 15% and bone height increased by 10% compared to baseline measurements. Group A showed minimal improvement. Conclusion: The incorporation of PRP as an adjunct to bone grafting in ARP following tooth extraction significantly enhances bone density and height, suggesting its efficacy in preserving the alveolar ridge. |
first_indexed | 2024-04-24T13:18:34Z |
format | Article |
id | doaj.art-c7874eeb40f04965bbd1c2bff8cba2af |
institution | Directory Open Access Journal |
issn | 0975-7406 |
language | English |
last_indexed | 2024-04-24T13:18:34Z |
publishDate | 2024-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Pharmacy and Bioallied Sciences |
spelling | doaj.art-c7874eeb40f04965bbd1c2bff8cba2af2024-04-04T16:37:40ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062024-01-0116556456610.4103/jpbs.jpbs_865_23The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extractionHiroj S BagdeMohammad K AlamYazan Eid Muteb AlmohammedSufyan Mohammed Mukhlef AlmaqawidAbdulelah Waheed Noman AlanaziFawaz Talal F. AlanaziMohammed G SghaireenBackground: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to bone grafting in ARP to enhance bone regeneration. Materials and Methods: A total of 60 patients requiring tooth extraction and ARP were included in this randomized controlled trial. Patients were divided into two groups: Group A received bone grafting alone, while Group B received bone grafting with PRP. Clinical and radiographic assessments were performed at baseline and 6-month postsurgery. Bone density and height were measured using arbitrary values. Results: At the 6-month follow-up, Group B demonstrated a statistically significant increase in bone density (P < 0.05) and bone height (P < 0.05) compared to Group A. The arbitrary values for bone density in Group B increased by 15% and bone height increased by 10% compared to baseline measurements. Group A showed minimal improvement. Conclusion: The incorporation of PRP as an adjunct to bone grafting in ARP following tooth extraction significantly enhances bone density and height, suggesting its efficacy in preserving the alveolar ridge.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagdealveolar ridge preservationbone graftingdental implantsefficacyplatelet-rich plasmatooth extraction |
spellingShingle | Hiroj S Bagde Mohammad K Alam Yazan Eid Muteb Almohammed Sufyan Mohammed Mukhlef Almaqawid Abdulelah Waheed Noman Alanazi Fawaz Talal F. Alanazi Mohammed G Sghaireen The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction Journal of Pharmacy and Bioallied Sciences alveolar ridge preservation bone grafting dental implants efficacy platelet-rich plasma tooth extraction |
title | The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
title_full | The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
title_fullStr | The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
title_full_unstemmed | The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
title_short | The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
title_sort | efficacy of platelet rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction |
topic | alveolar ridge preservation bone grafting dental implants efficacy platelet-rich plasma tooth extraction |
url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagde |
work_keys_str_mv | AT hirojsbagde theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT mohammadkalam theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT yazaneidmutebalmohammed theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT sufyanmohammedmukhlefalmaqawid theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT abdulelahwaheednomanalanazi theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT fawaztalalfalanazi theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT mohammedgsghaireen theefficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT hirojsbagde efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT mohammadkalam efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT yazaneidmutebalmohammed efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT sufyanmohammedmukhlefalmaqawid efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT abdulelahwaheednomanalanazi efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT fawaztalalfalanazi efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction AT mohammedgsghaireen efficacyofplateletrichplasmaasanadjuncttobonegraftinginalveolarridgepreservationfollowingtoothextraction |