The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction

Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to...

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Main Authors: Hiroj S Bagde, Mohammad K Alam, Yazan Eid Muteb Almohammed, Sufyan Mohammed Mukhlef Almaqawid, Abdulelah Waheed Noman Alanazi, Fawaz Talal F. Alanazi, Mohammed G Sghaireen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagde
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author Hiroj S Bagde
Mohammad K Alam
Yazan Eid Muteb Almohammed
Sufyan Mohammed Mukhlef Almaqawid
Abdulelah Waheed Noman Alanazi
Fawaz Talal F. Alanazi
Mohammed G Sghaireen
author_facet Hiroj S Bagde
Mohammad K Alam
Yazan Eid Muteb Almohammed
Sufyan Mohammed Mukhlef Almaqawid
Abdulelah Waheed Noman Alanazi
Fawaz Talal F. Alanazi
Mohammed G Sghaireen
author_sort Hiroj S Bagde
collection DOAJ
description Background: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to bone grafting in ARP to enhance bone regeneration. Materials and Methods: A total of 60 patients requiring tooth extraction and ARP were included in this randomized controlled trial. Patients were divided into two groups: Group A received bone grafting alone, while Group B received bone grafting with PRP. Clinical and radiographic assessments were performed at baseline and 6-month postsurgery. Bone density and height were measured using arbitrary values. Results: At the 6-month follow-up, Group B demonstrated a statistically significant increase in bone density (P < 0.05) and bone height (P < 0.05) compared to Group A. The arbitrary values for bone density in Group B increased by 15% and bone height increased by 10% compared to baseline measurements. Group A showed minimal improvement. Conclusion: The incorporation of PRP as an adjunct to bone grafting in ARP following tooth extraction significantly enhances bone density and height, suggesting its efficacy in preserving the alveolar ridge.
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spelling doaj.art-c7874eeb40f04965bbd1c2bff8cba2af2024-04-04T16:37:40ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062024-01-0116556456610.4103/jpbs.jpbs_865_23The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extractionHiroj S BagdeMohammad K AlamYazan Eid Muteb AlmohammedSufyan Mohammed Mukhlef AlmaqawidAbdulelah Waheed Noman AlanaziFawaz Talal F. AlanaziMohammed G SghaireenBackground: Tooth extraction often results in bone loss in the alveolar ridge, which can complicate subsequent dental implant placement. Alveolar ridge preservation (ARP) techniques, such as bone grafting, aim to mitigate this bone loss. Platelet-rich plasma (PRP) has been proposed as an adjunct to bone grafting in ARP to enhance bone regeneration. Materials and Methods: A total of 60 patients requiring tooth extraction and ARP were included in this randomized controlled trial. Patients were divided into two groups: Group A received bone grafting alone, while Group B received bone grafting with PRP. Clinical and radiographic assessments were performed at baseline and 6-month postsurgery. Bone density and height were measured using arbitrary values. Results: At the 6-month follow-up, Group B demonstrated a statistically significant increase in bone density (P < 0.05) and bone height (P < 0.05) compared to Group A. The arbitrary values for bone density in Group B increased by 15% and bone height increased by 10% compared to baseline measurements. Group A showed minimal improvement. Conclusion: The incorporation of PRP as an adjunct to bone grafting in ARP following tooth extraction significantly enhances bone density and height, suggesting its efficacy in preserving the alveolar ridge.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagdealveolar ridge preservationbone graftingdental implantsefficacyplatelet-rich plasmatooth extraction
spellingShingle Hiroj S Bagde
Mohammad K Alam
Yazan Eid Muteb Almohammed
Sufyan Mohammed Mukhlef Almaqawid
Abdulelah Waheed Noman Alanazi
Fawaz Talal F. Alanazi
Mohammed G Sghaireen
The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
Journal of Pharmacy and Bioallied Sciences
alveolar ridge preservation
bone grafting
dental implants
efficacy
platelet-rich plasma
tooth extraction
title The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
title_full The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
title_fullStr The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
title_full_unstemmed The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
title_short The efficacy of platelet-rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
title_sort efficacy of platelet rich plasma as an adjunct to bone grafting in alveolar ridge preservation following tooth extraction
topic alveolar ridge preservation
bone grafting
dental implants
efficacy
platelet-rich plasma
tooth extraction
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=564;epage=566;aulast=Bagde
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