Phosphorylation of RCC1 on Serine 11 Facilitates G1/S Transition in HPV E7-Expressing Cells

Phosphorylation of RCC1 on Serine 11 Facilitates G1/S Transition in HPV E7-Expressing Cells

Persistent infection of high-risk human papillomavirus (HR-HPV) plays a causal role in cervical cancer. Regulator of chromosome condensation 1 (RCC1) is a critical cell cycle regulator, which undergoes a few post-translational modifications including phosphorylation. Here, we showed that serine 11 (...

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Bibliographic Details
Main Authors: Xiaoyan Hou, Lijun Qiao, Ruijuan Liu, Xuechao Han, Weifang Zhang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
HPV
cervical cancer
RCC1
G1/S transition
phosphorylation
Online Access:https://www.mdpi.com/2218-273X/11/7/995

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