Independent validation of the prognostic value of cancer stem cell marker expression and hypoxia-induced gene expression for patients with locally advanced HNSCC after postoperative radiotherapy

Independent validation of the prognostic value of cancer stem cell marker expression and hypoxia-induced gene expression for patients with locally advanced HNSCC after postoperative radiotherapy

Objective: To validate the impact of HPV status, cancer stem cell (CSC) marker expression and tumour hypoxia status in patients with locally advanced head and neck squamous cell carcinoma (HNSCC), who received postoperative radiotherapy. The results of the exploration cohort have previously been rep...

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Bibliographic Details
Main Authors: Annett Linge, Steffen Löck, Constanze Krenn, Steffen Appold, Fabian Lohaus, Alexander Nowak, Volker Gudziol, Gustavo B. Baretton, Frank Buchholz, Michael Baumann, Mechthild Krause
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Biomarker
Cancer stem cells
HNSCC
HPV
Hypoxia
Postoperative radiochemotherapy
Validation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630816300064

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