Spatiotemporal dynamics exhibited by horizontal basal cells reveal a pro-neurogenic pathway during injury-induced olfactory epithelium regeneration

Summary: Horizontal basal cells (HBCs) mediate olfactory epithelium (OE) regeneration following severe tissue injury. The dynamism of the post-injury environment is well illustrated by in silico modeling of RNA sequencing data that demonstrate an evolving HBC transcriptome. Unfortunately, spatiotemp...

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Bibliographic Details
Main Authors: Jonathan D. Louie, Camila M. Barrios-Camacho, Benjamin H. Bromberg, Constantin A. Hintschich, James E. Schwob
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224008228