Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved?
Background: Leprosy or “Hansen Disease” is chronic inflammatory disease caused by Mycobacterium leprae. This disease is the oldest disease known to mankind. Leprosy is also known as “Kushtaroga.”. Leprosy was considered as an eradicated disease in 2005 but still a large number of leprosy cases are b...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Manipal College of Medical Sciences, Pokhara
2022-12-01
|
| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/46493 |
| _version_ | 1828125033454632960 |
|---|---|
| author | Deepti Gangwar Amitosh Mishra Sara Siddiqui Sangeeta Bohara Bushra Khanam |
| author_facet | Deepti Gangwar Amitosh Mishra Sara Siddiqui Sangeeta Bohara Bushra Khanam |
| author_sort | Deepti Gangwar |
| collection | DOAJ |
| description | Background: Leprosy or “Hansen Disease” is chronic inflammatory disease caused by Mycobacterium leprae. This disease is the oldest disease known to mankind. Leprosy is also known as “Kushtaroga.”. Leprosy was considered as an eradicated disease in 2005 but still a large number of leprosy cases are being reported in India.
Aims and Objectives: The aim of the study was to demonstrate that leprosy even being eradicated continuous to be a major health concern with changing trends.
Materials and Methods: This study is a a hospital-based crossectional study; it involves all new patients of leprosy attending dermatology O.P.D HIMS, Safedabad, Barabanki, U.P. from 2015 to 2016. The cases were classified as per Ridley – jopling classification. Skin biopsies were taken from all clinically suspected cases of leprosy and these biopsies were studied using H&E stain.
Results: In our study, 53 leprosy cases were registered from April 2015 to April 2016. According to demographic details of leprosy cases, maximum number of cases were in the age group 31–40 years 38.9% and in individuals <20 years 10.5%. Majority of cases were males (11.3%). The family history of leprosy was present in 9.4% of patients. Hypopigmented lesion on skin was most common symptom (32.1%). TT was most common clinical diagnosis (26.4%). IL was common histopathological diagnosis (26.4%). Atrophy of epidermis was seen in 50.9% of patients. Paucibacillary was seen in 62.3% of patients. Most of the cases were from Safedabad.
Conclusion: Leprosy although reported to be eradicated still continues to be one of the common communicable disease in Uttar Pradesh, India. This necessitates to strengthen screening of cases, early detection, and revival of our knowledge regarding the disease. |
| first_indexed | 2024-04-11T15:14:11Z |
| format | Article |
| id | doaj.art-c792d277a8534731ae241d3eba0da28c |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-11T15:14:11Z |
| publishDate | 2022-12-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-c792d277a8534731ae241d3eba0da28c2022-12-22T04:16:32ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-12-011312144148https://doi.org/10.3126/ajms.v13i12.46493Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved?Deepti Gangwar 0https://orcid.org/0000-0002-2918-1365Amitosh Mishra 1https://orcid.org/0000-0003-3393-9682Sara Siddiqui 2https://orcid.org/0000-0001-7085-5571Sangeeta Bohara 3https://orcid.org/0000-0002-7054-6805Bushra Khanam 4https://orcid.org/0000-0003-2644-6695Assistant Professor, Department of Pathology, Integral Institute of Medical Science and Research, Lucknow, Uttar Pradesh, India Assistant Professor, Department of Orthopedics, Integral Institute of Medical Science and Research, Lucknow, Uttar Pradesh, India Assistant Professor, Department of Physiology, Integral Institute of Medical Science and Research, Lucknow, Uttar Pradesh, India Professor, Department of Pathology, Hind Institute of Medical Sciences, Lucknow, Uttar Pradesh, India Tutor, Department of Pathology, Integral Institute of Medical Science and Research, Lucknow, Uttar Pradesh, India Background: Leprosy or “Hansen Disease” is chronic inflammatory disease caused by Mycobacterium leprae. This disease is the oldest disease known to mankind. Leprosy is also known as “Kushtaroga.”. Leprosy was considered as an eradicated disease in 2005 but still a large number of leprosy cases are being reported in India. Aims and Objectives: The aim of the study was to demonstrate that leprosy even being eradicated continuous to be a major health concern with changing trends. Materials and Methods: This study is a a hospital-based crossectional study; it involves all new patients of leprosy attending dermatology O.P.D HIMS, Safedabad, Barabanki, U.P. from 2015 to 2016. The cases were classified as per Ridley – jopling classification. Skin biopsies were taken from all clinically suspected cases of leprosy and these biopsies were studied using H&E stain. Results: In our study, 53 leprosy cases were registered from April 2015 to April 2016. According to demographic details of leprosy cases, maximum number of cases were in the age group 31–40 years 38.9% and in individuals <20 years 10.5%. Majority of cases were males (11.3%). The family history of leprosy was present in 9.4% of patients. Hypopigmented lesion on skin was most common symptom (32.1%). TT was most common clinical diagnosis (26.4%). IL was common histopathological diagnosis (26.4%). Atrophy of epidermis was seen in 50.9% of patients. Paucibacillary was seen in 62.3% of patients. Most of the cases were from Safedabad. Conclusion: Leprosy although reported to be eradicated still continues to be one of the common communicable disease in Uttar Pradesh, India. This necessitates to strengthen screening of cases, early detection, and revival of our knowledge regarding the disease.https://www.nepjol.info/index.php/AJMS/article/view/46493leprosy; post-eradication; biopsies |
| spellingShingle | Deepti Gangwar Amitosh Mishra Sara Siddiqui Sangeeta Bohara Bushra Khanam Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? Asian Journal of Medical Sciences leprosy; post-eradication; biopsies |
| title | Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? |
| title_full | Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? |
| title_fullStr | Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? |
| title_full_unstemmed | Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? |
| title_short | Leprosy in posteradication era – A clinicopathological correlation: How far we have achieved? |
| title_sort | leprosy in posteradication era a clinicopathological correlation how far we have achieved |
| topic | leprosy; post-eradication; biopsies |
| url | https://www.nepjol.info/index.php/AJMS/article/view/46493 |
| work_keys_str_mv | AT deeptigangwar leprosyinposteradicationeraaclinicopathologicalcorrelationhowfarwehaveachieved AT amitoshmishra leprosyinposteradicationeraaclinicopathologicalcorrelationhowfarwehaveachieved AT sarasiddiqui leprosyinposteradicationeraaclinicopathologicalcorrelationhowfarwehaveachieved AT sangeetabohara leprosyinposteradicationeraaclinicopathologicalcorrelationhowfarwehaveachieved AT bushrakhanam leprosyinposteradicationeraaclinicopathologicalcorrelationhowfarwehaveachieved |