Repurposing levocetirizine hydrochloride loaded into cationic ceramide/phospholipid composite (CCPCs) for management of alopecia: central composite design optimization, in- silico and in-vivo studies

Repurposing levocetirizine hydrochloride loaded into cationic ceramide/phospholipid composite (CCPCs) for management of alopecia: central composite design optimization, in- silico and in-vivo studies

Levocetirizine hydrochloride (LVC) is an antihistaminic drug that is repurposed for the treatment of alopecia. This investigation is targeted for formulating LVC into cationic ceramide/phospholipid composite (CCPCs) for the management of alopecia. CCPCs were fabricated by ethanol-injection approach,...

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Bibliographic Details
Main Authors: Rofida Albash, Rania Moataz El-Dahmy, Mohammed I. A. Hamed, Khaled M. Darwish, Abdulrahman M. Alahdal, Amira B. Kassem, Abdurrahman M. Fahmy
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Alopecia
levocetirizine hydrochloride
in-silico study
ceramide
drug discovery
industrial development
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2108939

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