PAX4 enhances beta-cell differentiation of human embryonic stem cells.

PAX4 enhances beta-cell differentiation of human embryonic stem cells.

BACKGROUND:Human embryonic stem cells (HESC) readily differentiate into an apparently haphazard array of cell types, corresponding to all three germ layers, when their culture conditions are altered, for example by growth in suspension as aggregates known as embryoid bodies (EBs). However, this dive...

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Bibliographic Details
Main Authors: Chee Gee Liew, Nadia N Shah, Sarah J Briston, Ruth M Shepherd, Cheen Peen Khoo, Mark J Dunne, Harry D Moore, Karen E Cosgrove, Peter W Andrews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2262135?pdf=render

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