The Reciprocal Relationship between Osteoporosis and Renal Stones
Previous studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2...
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MDPI AG
2022-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/22/6614 |
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| author | So Young Kim Juyong Chung Doo Sik Park Dae Myoung Yoo Woo Jin Bang Hyo Geun Choi |
| author_facet | So Young Kim Juyong Chung Doo Sik Park Dae Myoung Yoo Woo Jin Bang Hyo Geun Choi |
| author_sort | So Young Kim |
| collection | DOAJ |
| description | Previous studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2015) was analyzed. In study I, 67,811 patients with osteoporosis and 67,811 control I participants were matched. The hazard ratio (HR) of osteoporosis for renal stones was calculated using stratified Cox proportional hazard models. In study II, 25,261 patients with renal stones and 101,044 control II participants were matched. The HR of renal stones for osteoporosis was estimated using stratified Cox proportional hazard models. In study I, 3.4% (2276/67,811) of osteoporosis patients and 2.5% (1696/67,811) of control I participants had renal stones. Osteoporosis patients had a 1.36 times higher HR for renal stones than control I participants (95% confidence intervals [CI] = 1.28–1.45). In study II, 9.2% (2319/25,261) of renal stone patients and 7.6% (7658/101,044) of control II participants had osteoporosis. Renal stone patients had a 1.26 times higher HR for osteoporosis than control II participants (95% CI = 1.21–1.32). Adults with osteoporosis had a higher risk of renal stones. Moreover, adults with renal stones had a higher risk of osteoporosis. |
| first_indexed | 2024-03-09T18:15:05Z |
| format | Article |
| id | doaj.art-c798488a045b4da18f8951551e397011 |
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| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T18:15:05Z |
| publishDate | 2022-11-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-c798488a045b4da18f8951551e3970112023-11-24T08:47:10ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011122661410.3390/jcm11226614The Reciprocal Relationship between Osteoporosis and Renal StonesSo Young Kim0Juyong Chung1Doo Sik Park2Dae Myoung Yoo3Woo Jin Bang4Hyo Geun Choi5Department of Otorhinolaryngology—Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, KoreaDepartment of Otorhinolaryngology—Head and Neck Surgery, Wonkwang University School of Medicine, Iksan 54538, KoreaDepartment of Otorhinolaryngology—Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, KoreaHallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, KoreaDepartment of Urology, Hallym Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, KoreaDepartment of Otorhinolaryngology—Head and Neck Surgery, Wonkwang University School of Medicine, Iksan 54538, KoreaPrevious studies have proposed an association between osteoporosis and renal stones. The current analyses intended to investigate the bidirectional relationship between osteoporosis and renal stones. The ≥40-year-old population in the National Health Insurance Service-Health Screening cohort (2002–2015) was analyzed. In study I, 67,811 patients with osteoporosis and 67,811 control I participants were matched. The hazard ratio (HR) of osteoporosis for renal stones was calculated using stratified Cox proportional hazard models. In study II, 25,261 patients with renal stones and 101,044 control II participants were matched. The HR of renal stones for osteoporosis was estimated using stratified Cox proportional hazard models. In study I, 3.4% (2276/67,811) of osteoporosis patients and 2.5% (1696/67,811) of control I participants had renal stones. Osteoporosis patients had a 1.36 times higher HR for renal stones than control I participants (95% confidence intervals [CI] = 1.28–1.45). In study II, 9.2% (2319/25,261) of renal stone patients and 7.6% (7658/101,044) of control II participants had osteoporosis. Renal stone patients had a 1.26 times higher HR for osteoporosis than control II participants (95% CI = 1.21–1.32). Adults with osteoporosis had a higher risk of renal stones. Moreover, adults with renal stones had a higher risk of osteoporosis.https://www.mdpi.com/2077-0383/11/22/6614urolithiasisosteoporosisrisk factorscase–control studiesepidemiology |
| spellingShingle | So Young Kim Juyong Chung Doo Sik Park Dae Myoung Yoo Woo Jin Bang Hyo Geun Choi The Reciprocal Relationship between Osteoporosis and Renal Stones Journal of Clinical Medicine urolithiasis osteoporosis risk factors case–control studies epidemiology |
| title | The Reciprocal Relationship between Osteoporosis and Renal Stones |
| title_full | The Reciprocal Relationship between Osteoporosis and Renal Stones |
| title_fullStr | The Reciprocal Relationship between Osteoporosis and Renal Stones |
| title_full_unstemmed | The Reciprocal Relationship between Osteoporosis and Renal Stones |
| title_short | The Reciprocal Relationship between Osteoporosis and Renal Stones |
| title_sort | reciprocal relationship between osteoporosis and renal stones |
| topic | urolithiasis osteoporosis risk factors case–control studies epidemiology |
| url | https://www.mdpi.com/2077-0383/11/22/6614 |
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