Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma

Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma

Women with scleroderma (SSc) maintain significantly higher quantities of persisting fetal microchimerism (FMc) from complete or incomplete pregnancies in their peripheral blood compared to healthy women. The non-classical class-I human leukocyte antigen (HLA) molecule HLA-G plays a pivotal role for...

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Bibliographic Details
Main Authors: Julie Di Cristofaro, Karlin R. Karlmark, Sami B. Kanaan, Doua F. Azzouz, Marina El Haddad, Lucas Hubert, Dominique Farge-Bancel, Brigitte Granel, Jean Robert Harlé, Eric Hachulla, Etienne Pardoux, Jean Roudier, Christophe Picard, Nathalie C. Lambert
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigen-G
microchimerism
scleroderma
systemic sclerosis
pregnancy
fetal
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01685/full

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